Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth
Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous population of myeloid cells in cancer patients and tumor-bearing mice that potently inhibits T cell responses. During tumor progression, MDSCs accumulate in several organs, including the tumor tissue. So far, tumor-infiltrating MDSC...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2012
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| In: |
The journal of immunology
Year: 2012, Jahrgang: 189, Heft: 12, Pages: 5602-5611 |
| ISSN: | 1550-6606 |
| DOI: | 10.4049/jimmunol.1201018 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.4049/jimmunol.1201018 Verlag, kostenfrei, Volltext: http://www.jimmunol.org/content/189/12/5602 
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| Verfasserangaben: | Eva Schlecker, Ana Stojanovic, Christian Eisen, Christian Quack, Christine S. Falk, Viktor Umansky, and Adelheid Cerwenka |