Do alcohol-dependent patients show different neural activation during response inhibition than healthy controls in an alcohol-related fMRI go/no-go-task?

Rationale Alcohol dependence is associated with impaired response inhibition and heightened cue reactivity towards alcohol-related stimuli. Several brain areas, but mainly prefrontal structures, have been linked to response inhibition in addiction. This study aimed at combining both aspects: salienc...

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Main Authors: Czapla, Marta (Author) , Bäuchl, Christian (Author) , Simon, Joe J. (Author) , Friederich, Hans-Christoph (Author) , Mann, Karl (Author) , Herpertz, Sabine (Author)
Format: Article (Journal)
Language:English
Published: 4 February 2017
In: Psychopharmacology
Year: 2017, Volume: 234, Issue: 6, Pages: 1001-1015
ISSN:1432-2072
DOI:10.1007/s00213-017-4541-9
Online Access:Verlag, Volltext: http://dx.doi.org/10.1007/s00213-017-4541-9
Verlag, Volltext: http://link.springer.com/10.1007/s00213-017-4541-9
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Author Notes:Marta Czapla, Christian Baeuchl, Joe J. Simon, Barbara Richter, Matthias Kluge, Hans-Christoph Friederich, Karl Mann, Sabine C. Herpertz, Sabine Loeber
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Summary:Rationale Alcohol dependence is associated with impaired response inhibition and heightened cue reactivity towards alcohol-related stimuli. Several brain areas, but mainly prefrontal structures, have been linked to response inhibition in addiction. This study aimed at combining both aspects: salience of drug-associated cues and response inhibition using a go/no-go task with alcohol-associated stimuli during functional magnetic resonance imaging (fMRI).
Item Description:Gesehen am 09.05.2018
Physical Description:Online Resource
ISSN:1432-2072
DOI:10.1007/s00213-017-4541-9