Antitumor effects of proteasome inhibition in anaplastic thyroid carcinoma

The ubiquitin-proteasome pathway has been identified as a potential molecular target for cancer therapy. In this study, we investigated the effect of the proteasome inhibitor bortezomib on anaplastic thyroid carcinoma (ATC) characterized by complete refractoriness to multimodal therapeutic approache...

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Bibliographic Details

Main Authors:	Altmann, Annette (Author) , Askoxylakis, Vasileios (Author) , Schöning, Tilman (Author) , Jesenofsky, Ralf (Author) , Haberkorn, Uwe (Author)
Format:	Article (Journal)
Language:	English
Published:	October 10, 2012
In:	Journal of nuclear medicine Year: 2012, Volume: 53, Issue: 11, Pages: 1764-1771
ISSN:	2159-662X
DOI:	10.2967/jnumed.111.101295
Online Access:	Verlag, kostenfrei, Volltext: http://dx.doi.org/10.2967/jnumed.111.101295
Author Notes:	Annette Altmann, Annette Markert, Vasileios Askoxylakis, Tilman Schöning, Ralf Jesenofsky, Michael Eisenhut and Uwe Haberkorn