Buchumschlag

The role of microRNAs in photodynamic therapy of cancer

Photodynamic therapy (PDT) is a non-invasive treatment modality used in the management of both benign and malignant conditions. It involves the administration of a photosensitizing agent followed by local light irradiation, which activates the photosensitizer, resulting in tissue damage. An in-depth...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: El-Daly, Sherien M. (VerfasserIn) , Abba, Mohammed L. (VerfasserIn) , Gamal-Eldeen, Amira M. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 15 December 2017
In: European journal of medicinal chemistry
Year: 2017, Jahrgang: 142, Pages: 550-555
ISSN:1768-3254
DOI:10.1016/j.ejmech.2017.10.011
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/j.ejmech.2017.10.011
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0223523417308036
Volltext
Verfasserangaben:Sherien M. El-Daly, Mohammed L. Abba, Amira M. Gamal-Eldeen

MARC

LEADER 00000caa a2200000 c 4500
001 1575185504
003 DE-627
005 20230427042903.0
007 cr uuu---uuuuu
008 180516s2017 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.ejmech.2017.10.011  |2 doi 
035 |a (DE-627)1575185504 
035 |a (DE-576)505185504 
035 |a (DE-599)BSZ505185504 
035 |a (OCoLC)1341009546 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a El-Daly, Sherien M.  |e VerfasserIn  |0 (DE-588)1159671826  |0 (DE-627)1022335456  |0 (DE-576)505185857  |4 aut 
245 1 4 |a The role of microRNAs in photodynamic therapy of cancer  |c Sherien M. El-Daly, Mohammed L. Abba, Amira M. Gamal-Eldeen 
264 1 |c 15 December 2017 
300 |a 6 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 16.05.2018 
520 |a Photodynamic therapy (PDT) is a non-invasive treatment modality used in the management of both benign and malignant conditions. It involves the administration of a photosensitizing agent followed by local light irradiation, which activates the photosensitizer, resulting in tissue damage. An in-depth understanding of the molecular mechanisms and mediators of PDT is important, not only for appreciating how this treatment modality is effective, but also as an avenue for understanding potential shortfalls and untoward effects that can be managed or improved. MicroRNAs are a group of endogenous small non-coding regulatory molecules that play important roles in regulating several physiological processes and have been implicated in several pathologies including cancer. They have been found to regulate key cellular pathways and their aberrant expression highlights not only disease onset or progression, but is associated with therapy resistance and disease outcome. In the present review, we evaluate the role of microRNAs in PDT and dissect their function as effectors of PDT including the molecules they regulate. We also look at how miRNA signatures can be used as predictors of therapy response to PDT and what implications this may have in the treatment of patients with PDT. 
650 4 |a Apoptosis 
650 4 |a Microarray 
650 4 |a MicroRNAs 
650 4 |a Photodynamic therapy 
650 4 |a Photosensitizers 
700 1 |a Abba, Mohammed L.  |d 1974-  |e VerfasserIn  |0 (DE-588)1024986101  |0 (DE-627)720854369  |0 (DE-576)369801407  |4 aut 
700 1 |a Gamal-Eldeen, Amira M.  |d 1969-  |e VerfasserIn  |0 (DE-588)123650267  |0 (DE-627)706382269  |0 (DE-576)293808066  |4 aut 
773 0 8 |i Enthalten in  |t European journal of medicinal chemistry  |d Amsterdam [u.a.] : Elsevier Science, 1987  |g 142(2017), Seite 550-555  |h Online-Ressource  |w (DE-627)320443213  |w (DE-600)2005170-0  |w (DE-576)25927125X  |x 1768-3254  |7 nnas  |a The role of microRNAs in photodynamic therapy of cancer 
773 1 8 |g volume:142  |g year:2017  |g pages:550-555  |g extent:6  |a The role of microRNAs in photodynamic therapy of cancer 
856 4 0 |u http://dx.doi.org/10.1016/j.ejmech.2017.10.011  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u http://www.sciencedirect.com/science/article/pii/S0223523417308036  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20180516 
993 |a Article 
994 |a 2017 
998 |g 1024986101  |a Abba, Mohammed L.  |m 1024986101:Abba, Mohammed L.  |d 60000  |d 61800  |e 60000PA1024986101  |e 61800PA1024986101  |k 0/60000/  |k 1/60000/61800/  |p 2 
999 |a KXP-PPN1575185504  |e 3009512678 
BIB |a Y 
SER |a journal 
JSO |a {"relHost":[{"language":["eng"],"part":{"year":"2017","text":"142(2017), Seite 550-555","pages":"550-555","extent":"6","volume":"142"},"note":["Gesehen am 22.11.04"],"title":[{"title":"European journal of medicinal chemistry","title_sort":"European journal of medicinal chemistry"}],"origin":[{"publisherPlace":"Amsterdam [u.a.]","dateIssuedDisp":"1987-","publisher":"Elsevier Science","dateIssuedKey":"1987"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"The role of microRNAs in photodynamic therapy of cancerEuropean journal of medicinal chemistry","id":{"issn":["1768-3254"],"eki":["320443213"],"zdb":["2005170-0"]},"recId":"320443213","pubHistory":["Nachgewiesen 22.1987 -"],"physDesc":[{"extent":"Online-Ressource"}]}],"id":{"doi":["10.1016/j.ejmech.2017.10.011"],"eki":["1575185504"]},"name":{"displayForm":["Sherien M. El-Daly, Mohammed L. Abba, Amira M. Gamal-Eldeen"]},"physDesc":[{"extent":"6 S."}],"recId":"1575185504","type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 16.05.2018"],"origin":[{"dateIssuedKey":"2017","dateIssuedDisp":"15 December 2017"}],"title":[{"title":"The role of microRNAs in photodynamic therapy of cancer","title_sort":"role of microRNAs in photodynamic therapy of cancer"}],"language":["eng"],"person":[{"family":"El-Daly","display":"El-Daly, Sherien M.","role":"aut","given":"Sherien M."},{"given":"Mohammed L.","role":"aut","family":"Abba","display":"Abba, Mohammed L."},{"family":"Gamal-Eldeen","display":"Gamal-Eldeen, Amira M.","role":"aut","given":"Amira M."}]} 
SRT |a ELDALYSHERROLEOFMICR1520 

Ähnliche Einträge