Vitamin A metabolism in benign and malignant melanocytic skin cells: importance of lecithin/retinol acyltransferase and RPE65
Disturbance in vitamin A metabolism seems to be an important attribute of cancer cells. Retinoids, particularly retinoic acid, have critical regulatory functions and appear to modulate tumor development and progression. The key step of vitamin A metabolism is the esterification of all-trans retinol,...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2012
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| In: |
Journal of cellular physiology
Year: 2012, Jahrgang: 227, Heft: 2, Pages: 718-728 |
| ISSN: | 1097-4652 |
| DOI: | 10.1002/jcp.22779 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1002/jcp.22779
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| Verfasserangaben: | Philipp M. Amann, Chonglin Luo, Robert W. Owen, Claudia Hofmann, Muriel Freudenberger, Dirk Schadendorf, Stefan B. Eichmüller, and Alexandr V. Bazhin |