NOTCH1 mutation, TP53 alteration and myeloid antigen expression predict outcome heterogeneity in children with first relapse of T-cell acute lymphoblastic leukemia
Relapse of T-cell acute lymphoblastic leukemia (T-ALL) has a dismal prognosis, with only 20% of afflicted children surviving. Children with relapsed T-ALL are commonly treated within high-risk arms of second-line treatment protocols that include mandatory hematopoietic stem cell transplantation (HSC...
Gespeichert in:
| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) Editorial |
| Sprache: | Englisch |
| Veröffentlicht: |
July 2017
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| In: |
Haematologica
Year: 2017, Jahrgang: 102, Heft: 7, Pages: e249-e252 |
| ISSN: | 1592-8721 |
| DOI: | 10.3324/haematol.2016.157792 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.3324/haematol.2016.157792 Verlag, Volltext: http://www.haematologica.org/content/102/7/e249 
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| Verfasserangaben: | Jana Hof, Corinne Kox, Stefanie Groeneveld-Krentz, Obul R. Bandapalli, Leonid Karawajew, Katharina Schedel, Joachim B. Kunz, Cornelia Eckert, Wolf-Dieter Ludwig, Richard Ratei, Peter Rhein, Günter Henze, Martina U. Muckenthaler, Andreas E. Kulozik, Arend von Stackelberg, Renate Kirschner-Schwabe |
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| 520 | |a Relapse of T-cell acute lymphoblastic leukemia (T-ALL) has a dismal prognosis, with only 20% of afflicted children surviving. Children with relapsed T-ALL are commonly treated within high-risk arms of second-line treatment protocols that include mandatory hematopoietic stem cell transplantation (HSCT) if a second complete remission can be induced. | ||
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