IVIM-DWI of transplanted kidneys: reduced diffusion and perfusion dependent on cold ischemia time
Purpose To evaluate the effect of cold ischemia time (CIT) of renal allografts on diffusion and perfusion using intravoxel incoherent motion (IVIM) derived parameters. Material and methods A total of 37 patients with renal allografts (CIT: 27 <15h, 10 ≥15h) and 30 individuals with healthy kidneys...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
10 July 2012
|
| In: |
European journal of radiology
Year: 2012, Jahrgang: 81, Heft: 9, Pages: e951-e956 |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2012.06.008 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.ejrad.2012.06.008 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0720048X12002756 
|
| Verfasserangaben: | S. Rheinheimer, F. Schneider, B. Stieltjes, C. Morath, M. Zeier, H.U. Kauczor, P. Hallscheidt |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1575784580 | ||
| 003 | DE-627 | ||
| 005 | 20220814150538.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180528s2012 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ejrad.2012.06.008 |2 doi | |
| 035 | |a (DE-627)1575784580 | ||
| 035 | |a (DE-576)505784580 | ||
| 035 | |a (DE-599)BSZ505784580 | ||
| 035 | |a (OCoLC)1341010015 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Rheinheimer, Stephan |d 1987- |e VerfasserIn |0 (DE-588)103838866X |0 (DE-627)757232450 |0 (DE-576)392380811 |4 aut | |
| 245 | 1 | 0 | |a IVIM-DWI of transplanted kidneys |b reduced diffusion and perfusion dependent on cold ischemia time |c S. Rheinheimer, F. Schneider, B. Stieltjes, C. Morath, M. Zeier, H.U. Kauczor, P. Hallscheidt |
| 264 | 1 | |c 10 July 2012 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 28.05.2018 | ||
| 520 | |a Purpose To evaluate the effect of cold ischemia time (CIT) of renal allografts on diffusion and perfusion using intravoxel incoherent motion (IVIM) derived parameters. Material and methods A total of 37 patients with renal allografts (CIT: 27 <15h, 10 ≥15h) and 30 individuals with healthy kidneys were examined at 1.5T using a single-shot echo-planar diffusion-weighted pulse sequence with nine b-values ranging from 0 to 800s/mm2. ADC, perfusion fraction f, and the diffusion coefficient D were calculated using the IVIM model. Parameters of allografts stratified by CIT were compared with healthy kidney groups using the Mann-Whitney U test for unpaired data. We computed the Spearman correlation coefficient for correlation with creatinine values. Results ADC, D, and f of transplanted kidneys were significantly lower than in the healthy controls. The long-CIT group showed significantly lower diffusion parameters compared with the short-CIT group [mean±SD]: ADC: 1.63±0.14μm2/ms, f: 11.90±5.22%, D: 1.55±0.25μm2/ms versus ADC: 1.79±0.13μm2/ms, f: 16.12±3.43%, D: 1.73±0.14μm2/ms, PADC, f, D<0.05. Conclusion Our results suggest that diffusion parameters, especially the ADC, depend on the CIT of the kidney allograft. Potentially, this stands for functional changes in renal allografts. Diffusion-weighted imaging could be used for follow-up examinations. Thus, diffusion parameters may help guide therapy in patients with delayed graft function. | ||
| 650 | 4 | |a ADC | |
| 650 | 4 | |a Diffusion | |
| 650 | 4 | |a Ischemia | |
| 650 | 4 | |a IVIM | |
| 650 | 4 | |a Kidney | |
| 650 | 4 | |a Renal | |
| 650 | 4 | |a Transplantation | |
| 700 | 1 | |a Morath, Christian |d 1973- |e VerfasserIn |0 (DE-588)124036155 |0 (DE-627)085595837 |0 (DE-576)293989923 |4 aut | |
| 700 | 1 | |a Zeier, Martin |e VerfasserIn |0 (DE-588)1026480302 |0 (DE-627)726772356 |0 (DE-576)371826438 |4 aut | |
| 700 | 1 | |a Kauczor, Hans-Ulrich |d 1962- |e VerfasserIn |0 (DE-588)139267123 |0 (DE-627)70327113X |0 (DE-576)310955327 |4 aut | |
| 700 | 1 | |a Hallscheidt, Peter |e VerfasserIn |0 (DE-588)1072530686 |0 (DE-627)827694156 |0 (DE-576)173264670 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of radiology |d Amsterdam [u.a.] : Elsevier Science, 1990 |g 81(2012), 9, Seite e951-e956 |h Online-Ressource |w (DE-627)32044483X |w (DE-600)2005350-2 |w (DE-576)099718138 |x 1872-7727 |7 nnas |a IVIM-DWI of transplanted kidneys reduced diffusion and perfusion dependent on cold ischemia time |
| 773 | 1 | 8 | |g volume:81 |g year:2012 |g number:9 |g pages:e951-e956 |g extent:6 |a IVIM-DWI of transplanted kidneys reduced diffusion and perfusion dependent on cold ischemia time |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.ejrad.2012.06.008 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S0720048X12002756 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180528 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 1072530686 |a Hallscheidt, Peter |m 1072530686:Hallscheidt, Peter |d 910000 |d 911400 |e 910000PH1072530686 |e 911400PH1072530686 |k 0/910000/ |k 1/910000/911400/ |p 7 |y j | ||
| 998 | |g 139267123 |a Kauczor, Hans-Ulrich |m 139267123:Kauczor, Hans-Ulrich |d 910000 |d 911400 |e 910000PK139267123 |e 911400PK139267123 |k 0/910000/ |k 1/910000/911400/ |p 6 | ||
| 998 | |g 1026480302 |a Zeier, Martin |m 1026480302:Zeier, Martin |d 910000 |d 910100 |e 910000PZ1026480302 |e 910100PZ1026480302 |k 0/910000/ |k 1/910000/910100/ |p 5 | ||
| 998 | |g 124036155 |a Morath, Christian |m 124036155:Morath, Christian |d 50000 |e 50000PM124036155 |k 0/50000/ |p 4 | ||
| 998 | |g 103838866X |a Rheinheimer, Stephan |m 103838866X:Rheinheimer, Stephan |d 910000 |d 911400 |e 910000PR103838866X |e 911400PR103838866X |k 0/910000/ |k 1/910000/911400/ |p 1 |x j | ||
| 999 | |a KXP-PPN1575784580 |e 3010574010 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"family":"Rheinheimer","given":"Stephan","role":"aut","display":"Rheinheimer, Stephan"},{"family":"Morath","given":"Christian","role":"aut","display":"Morath, Christian"},{"display":"Zeier, Martin","family":"Zeier","role":"aut","given":"Martin"},{"role":"aut","given":"Hans-Ulrich","family":"Kauczor","display":"Kauczor, Hans-Ulrich"},{"display":"Hallscheidt, Peter","role":"aut","given":"Peter","family":"Hallscheidt"}],"relHost":[{"id":{"zdb":["2005350-2"],"issn":["1872-7727"],"eki":["32044483X"]},"part":{"extent":"6","text":"81(2012), 9, Seite e951-e956","issue":"9","pages":"e951-e956","volume":"81","year":"2012"},"titleAlt":[{"title":"EJR"}],"pubHistory":["Nachgewiesen 10.1990 -"],"title":[{"subtitle":"EJR","title":"European journal of radiology","title_sort":"European journal of radiology"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"note":["Gesehen am 05.02.20"],"origin":[{"publisherPlace":"Amsterdam [u.a.]","dateIssuedKey":"1990","dateIssuedDisp":"1990-","publisher":"Elsevier Science"}],"disp":"IVIM-DWI of transplanted kidneys reduced diffusion and perfusion dependent on cold ischemia timeEuropean journal of radiology","recId":"32044483X","physDesc":[{"extent":"Online-Ressource"}]}],"origin":[{"dateIssuedDisp":"10 July 2012","dateIssuedKey":"2012"}],"note":["Gesehen am 28.05.2018"],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"title":[{"subtitle":"reduced diffusion and perfusion dependent on cold ischemia time","title_sort":"IVIM-DWI of transplanted kidneys","title":"IVIM-DWI of transplanted kidneys"}],"physDesc":[{"extent":"6 S."}],"recId":"1575784580","name":{"displayForm":["S. Rheinheimer, F. Schneider, B. Stieltjes, C. Morath, M. Zeier, H.U. Kauczor, P. Hallscheidt"]},"id":{"eki":["1575784580"],"doi":["10.1016/j.ejrad.2012.06.008"]}} | ||
| SRT | |a RHEINHEIMEIVIMDWIOFT1020 | ||