Non-invasive diagnosis of hepatocellular carcinoma revisited
We read with interest the recent work by Ho et al demonstrating mutational hyperactivation of mammalian target of rapamycin signalling in a subgroup of hepatocellular carcinoma (HCC).1 As Berasain and Lechel concluded that the prospect of a positive therapeutic response may outweigh the risk associa...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) Editorial |
| Sprache: | Englisch |
| Veröffentlicht: |
2018
|
| In: |
Gut
Year: 2017, Jahrgang: 67, Heft: 5, Pages: 991-993 |
| ISSN: | 1468-3288 |
| DOI: | 10.1136/gutjnl-2017-314981 |
| Online-Zugang: | Verlag, Pay-per-use, Volltext: http://dx.doi.org/10.1136/gutjnl-2017-314981 Verlag, Pay-per-use, Volltext: http://gut.bmj.com/content/67/5/991 
|
| Verfasserangaben: | Cora Mueller, Nina Waldburger, Ulrike Stampfl, Hans-Ulrich Kauczor, Peter Schirmacher, Christof Matthias Sommer, Thomas Longerich |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1575807610 | ||
| 003 | DE-627 | ||
| 005 | 20240316100355.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180529r20182017xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1136/gutjnl-2017-314981 |2 doi | |
| 035 | |a (DE-627)1575807610 | ||
| 035 | |a (DE-576)505807610 | ||
| 035 | |a (DE-599)BSZ505807610 | ||
| 035 | |a (OCoLC)1341010297 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Müller, Cora |e VerfasserIn |0 (DE-588)1160258678 |0 (DE-627)102359448X |0 (DE-576)505807513 |4 aut | |
| 245 | 1 | 0 | |a Non-invasive diagnosis of hepatocellular carcinoma revisited |c Cora Mueller, Nina Waldburger, Ulrike Stampfl, Hans-Ulrich Kauczor, Peter Schirmacher, Christof Matthias Sommer, Thomas Longerich |
| 264 | 1 | |c 2018 | |
| 300 | |a 3 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Published online first: 12 september 2017 | ||
| 500 | |a Gesehen am 06.05.2019 | ||
| 520 | |a We read with interest the recent work by Ho et al demonstrating mutational hyperactivation of mammalian target of rapamycin signalling in a subgroup of hepatocellular carcinoma (HCC).1 As Berasain and Lechel concluded that the prospect of a positive therapeutic response may outweigh the risk associated with the HCC biopsy procedure2 and histology is essential for confirming a diagnosis of intrahepatic cholangiocarcinoma (ICC),3 we revisited the performance of non-invasive HCC diagnosis as recommended by current guidelines (eg, American Association for the Study of Liver Diseases (AASLD)) in clinical practice. 4 We retrospectively analysed all patients (n=182) in which a CT-guided liver biopsy was performed at a tertiary referral centre within a 9-year period due to the clinical differential diagnosis of HCC. After quality control, a total of 94 biopsies (figure 1A, see online supplementary table 1) could be evaluated. HCC development was associated with the presence of cirrhosis (n=51/65, p<0.001), which was also found in 27% (3/11) of ICC and 33% (1/3) of combined hepatocellular-cholangiocarcinoma (HCC-CC) patients. The number of false-positive non-invasive HCC diagnosis was higher in patients without cirrhosis (n=13/19; table … | ||
| 534 | |c 2017 | ||
| 650 | 4 | |a hepatocellular carcinoma | |
| 650 | 4 | |a liver biopsy | |
| 650 | 4 | |a liver imaging | |
| 700 | 1 | |a Waldburger, Nina |d 1981- |e VerfasserIn |0 (DE-588)1020629487 |0 (DE-627)691283729 |0 (DE-576)359028365 |4 aut | |
| 700 | 1 | |a Stampfl, Ulrike |d 1978- |e VerfasserIn |0 (DE-588)132557711 |0 (DE-627)523645104 |0 (DE-576)261999664 |4 aut | |
| 700 | 1 | |a Kauczor, Hans-Ulrich |d 1962- |e VerfasserIn |0 (DE-588)139267123 |0 (DE-627)70327113X |0 (DE-576)310955327 |4 aut | |
| 700 | 1 | |a Schirmacher, Peter |d 1961- |e VerfasserIn |0 (DE-588)1020440112 |0 (DE-627)691221197 |0 (DE-576)360427448 |4 aut | |
| 700 | 1 | |a Sommer, Christof-Matthias |d 1978- |e VerfasserIn |0 (DE-588)133929701 |0 (DE-627)558738699 |0 (DE-576)278278035 |4 aut | |
| 700 | 1 | |a Longerich, Thomas |d 1974- |e VerfasserIn |0 (DE-588)128494514 |0 (DE-627)373916124 |0 (DE-576)297178059 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Gut |d London : BMJ Publishing Group, 1960 |g 67(2018), 5, Seite 991-993 |h Online-Ressource |w (DE-627)302725628 |w (DE-600)1492637-4 |w (DE-576)082435405 |x 1468-3288 |7 nnas |a Non-invasive diagnosis of hepatocellular carcinoma revisited |
| 773 | 1 | 8 | |g volume:67 |g year:2018 |g number:5 |g pages:991-993 |g extent:3 |a Non-invasive diagnosis of hepatocellular carcinoma revisited |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1136/gutjnl-2017-314981 |x Verlag |x Resolving-System |z Pay-per-use |3 Volltext |
| 856 | 4 | 0 | |u http://gut.bmj.com/content/67/5/991 |x Verlag |z Pay-per-use |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180529 | ||
| 993 | |a Editorial | ||
| 994 | |a 2018 | ||
| 998 | |g 128494514 |a Longerich, Thomas |m 128494514:Longerich, Thomas |d 910000 |d 912000 |e 910000PL128494514 |e 912000PL128494514 |k 0/910000/ |k 1/910000/912000/ |p 7 |y j | ||
| 998 | |g 133929701 |a Sommer, Christof-Matthias |m 133929701:Sommer, Christof-Matthias |d 910000 |d 911400 |e 910000PS133929701 |e 911400PS133929701 |k 0/910000/ |k 1/910000/911400/ |p 6 | ||
| 998 | |g 1020440112 |a Schirmacher, Peter |m 1020440112:Schirmacher, Peter |d 910000 |d 912000 |d 700000 |d 718000 |e 910000PS1020440112 |e 912000PS1020440112 |e 700000PS1020440112 |e 718000PS1020440112 |k 0/910000/ |k 1/910000/912000/ |k 0/700000/ |k 1/700000/718000/ |p 5 | ||
| 998 | |g 139267123 |a Kauczor, Hans-Ulrich |m 139267123:Kauczor, Hans-Ulrich |d 910000 |d 911400 |e 910000PK139267123 |e 911400PK139267123 |k 0/910000/ |k 1/910000/911400/ |p 4 | ||
| 998 | |g 132557711 |a Stampfl, Ulrike |m 132557711:Stampfl, Ulrike |d 50000 |e 50000PS132557711 |k 0/50000/ |p 3 | ||
| 998 | |g 1020629487 |a Waldburger, Nina |m 1020629487:Waldburger, Nina |p 2 | ||
| 998 | |g 1160258678 |a Müller, Cora |m 1160258678:Müller, Cora |d 910000 |d 912000 |e 910000PM1160258678 |e 912000PM1160258678 |k 0/910000/ |k 1/910000/912000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1575807610 |e 3010616457 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"3 S."}],"recId":"1575807610","note":["Published online first: 12 september 2017","Gesehen am 06.05.2019"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"language":["eng"],"title":[{"title":"Non-invasive diagnosis of hepatocellular carcinoma revisited","title_sort":"Non-invasive diagnosis of hepatocellular carcinoma revisited"}],"relHost":[{"recId":"302725628","physDesc":[{"extent":"Online-Ressource"}],"disp":"Non-invasive diagnosis of hepatocellular carcinoma revisitedGut","origin":[{"publisher":"BMJ Publishing Group","dateIssuedKey":"1960","publisherPlace":"London","dateIssuedDisp":"1960-"}],"title":[{"subtitle":"an international journal of gastroenterology and hepatology","title":"Gut","title_sort":"Gut"}],"language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"note":["Gesehen am 07.09.12"],"pubHistory":["1.1960 -"],"titleAlt":[{"title":"Gut online"},{"title":"eGut"}],"id":{"issn":["1468-3288"],"eki":["302725628"],"zdb":["1492637-4"]},"part":{"pages":"991-993","issue":"5","text":"67(2018), 5, Seite 991-993","extent":"3","year":"2018","volume":"67"}}],"person":[{"display":"Müller, Cora","family":"Müller","role":"aut","given":"Cora"},{"display":"Waldburger, Nina","given":"Nina","role":"aut","family":"Waldburger"},{"given":"Ulrike","role":"aut","family":"Stampfl","display":"Stampfl, Ulrike"},{"display":"Kauczor, Hans-Ulrich","family":"Kauczor","role":"aut","given":"Hans-Ulrich"},{"family":"Schirmacher","role":"aut","given":"Peter","display":"Schirmacher, Peter"},{"display":"Sommer, Christof-Matthias","role":"aut","given":"Christof-Matthias","family":"Sommer"},{"given":"Thomas","role":"aut","family":"Longerich","display":"Longerich, Thomas"}],"origin":[{"dateIssuedKey":"2018","dateIssuedDisp":"2018"}],"id":{"doi":["10.1136/gutjnl-2017-314981"],"eki":["1575807610"]},"name":{"displayForm":["Cora Mueller, Nina Waldburger, Ulrike Stampfl, Hans-Ulrich Kauczor, Peter Schirmacher, Christof Matthias Sommer, Thomas Longerich"]}} | ||
| SRT | |a MUELLERCORNONINVASIV2018 | ||