Changing the tumor microenvironment: new strategies for immunotherapy
Solid tumors are composed of malignant cells surrounded by a tumor-conditioned stroma that contains extracellular matrix and a variety of nonmalignant populations, including myeloid cells, lymphocytes, fibroblasts, and endothelial cells. These stromal elements form a local immunoregulatory network t...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
July 23, 2012
|
| In: |
Cancer research
Year: 2012, Jahrgang: 72, Heft: 20, Pages: 5159-5164 |
| ISSN: | 1538-7445 |
| DOI: | 10.1158/0008-5472.CAN-12-1952 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1158/0008-5472.CAN-12-1952 Verlag, kostenfrei, Volltext: http://cancerres.aacrjournals.org/content/72/20/5159 
|
| Verfasserangaben: | Pedro Berraondo, Viktor Umansky, and Ignacio Melero |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1575841835 | ||
| 003 | DE-627 | ||
| 005 | 20220814151617.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180530s2012 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1158/0008-5472.CAN-12-1952 |2 doi | |
| 035 | |a (DE-627)1575841835 | ||
| 035 | |a (DE-576)505841835 | ||
| 035 | |a (DE-599)BSZ505841835 | ||
| 035 | |a (OCoLC)1341010355 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Berraondo, Pedro |e VerfasserIn |0 (DE-588)1160316066 |0 (DE-627)1023463334 |0 (DE-576)505840553 |4 aut | |
| 245 | 1 | 0 | |a Changing the tumor microenvironment |b new strategies for immunotherapy |c Pedro Berraondo, Viktor Umansky, and Ignacio Melero |
| 264 | 1 | |c July 23, 2012 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 30.05.2018 | ||
| 520 | |a Solid tumors are composed of malignant cells surrounded by a tumor-conditioned stroma that contains extracellular matrix and a variety of nonmalignant populations, including myeloid cells, lymphocytes, fibroblasts, and endothelial cells. These stromal elements form a local immunoregulatory network that must be overcome to achieve eradication of established tumors by immunotherapy. On March 21-22, 2012, a symposium was held in Pamplona, Spain, to share the recent advances regarding the molecules and cells that create and sustain this immune-hostile tumor microenvironment. Excellent targets for immunotherapeutic intervention were identified, and a number of therapeutic strategies under translation from mouse to human were presented. Cancer Res; 72(20); 5159-64. ©2012 AACR. | ||
| 700 | 1 | |a Umansky, Viktor |d 1955- |e VerfasserIn |0 (DE-588)102885756X |0 (DE-627)731733207 |0 (DE-576)376300078 |4 aut | |
| 700 | 1 | |a Melero, Ignacio |d 1964- |e VerfasserIn |0 (DE-588)1160316406 |0 (DE-627)1023463792 |0 (DE-576)505841118 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cancer research |d Philadelphia, Pa. : AACR, 1941 |g 72(2012), 20, Seite 5159-5164 |h Online-Ressource |w (DE-627)325489955 |w (DE-600)2036785-5 |w (DE-576)094502226 |x 1538-7445 |7 nnas |a Changing the tumor microenvironment new strategies for immunotherapy |
| 773 | 1 | 8 | |g volume:72 |g year:2012 |g number:20 |g pages:5159-5164 |g extent:6 |a Changing the tumor microenvironment new strategies for immunotherapy |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1158/0008-5472.CAN-12-1952 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u http://cancerres.aacrjournals.org/content/72/20/5159 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180530 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 102885756X |a Umansky, Viktor |m 102885756X:Umansky, Viktor |d 60000 |d 61900 |d 140000 |e 60000PU102885756X |e 61900PU102885756X |e 140000PU102885756X |k 0/60000/ |k 1/60000/61900/ |k 0/140000/ |p 2 | ||
| 999 | |a KXP-PPN1575841835 |e 3010798253 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"family":"Berraondo","display":"Berraondo, Pedro","role":"aut","given":"Pedro"},{"display":"Umansky, Viktor","family":"Umansky","given":"Viktor","role":"aut"},{"display":"Melero, Ignacio","family":"Melero","given":"Ignacio","role":"aut"}],"language":["eng"],"title":[{"title_sort":"Changing the tumor microenvironment","subtitle":"new strategies for immunotherapy","title":"Changing the tumor microenvironment"}],"origin":[{"dateIssuedDisp":"July 23, 2012","dateIssuedKey":"2012"}],"note":["Gesehen am 30.05.2018"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"physDesc":[{"extent":"6 S."}],"name":{"displayForm":["Pedro Berraondo, Viktor Umansky, and Ignacio Melero"]},"relHost":[{"corporate":[{"display":"American Association for Cancer Research","role":"isb"}],"language":["eng"],"part":{"text":"72(2012), 20, Seite 5159-5164","issue":"20","pages":"5159-5164","year":"2012","extent":"6","volume":"72"},"title":[{"title_sort":"Cancer research","title":"Cancer research"}],"pubHistory":["Volume 1, issue 1 (1 January 1941)-"],"note":["Gesehen am 31.03.25","Fortsetzung der Druck-Ausgabe"],"origin":[{"publisherPlace":"Philadelphia, Pa.","dateIssuedKey":"1941","publisher":"AACR","dateIssuedDisp":"1941-"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Changing the tumor microenvironment new strategies for immunotherapyCancer research","physDesc":[{"extent":"Online-Ressource"}],"name":{"displayForm":["American Association for Cancer Research"]},"recId":"325489955","id":{"issn":["1538-7445"],"zdb":["2036785-5"],"eki":["325489955"]}}],"recId":"1575841835","id":{"eki":["1575841835"],"doi":["10.1158/0008-5472.CAN-12-1952"]}} | ||
| SRT | |a BERRAONDOPCHANGINGTH2320 | ||