Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation
No specific drugs are currently available against hepatitis delta virus (HDV), a defective virus leading to the most severe form of chronic viral hepatitis in man. The lack of convenient HDV infection models has hampered the development of effective therapeutics. In this study, naïve and hepatitis...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2012
|
| In: |
Hepatology
Year: 2011, Jahrgang: 55, Heft: 3, Pages: 685-694 |
| ISSN: | 1527-3350 |
| DOI: | 10.1002/hep.24758 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1002/hep.24758 Verlag, kostenfrei, Volltext: https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.24758 |
| Verfasserangaben: | Marc Lütgehetmann, Lida V. Mancke, Tassilo Volz, Martina Helbig, Lena Allweiss, Till Bornscheuer, Joerg M. Pollok, Ansgar W. Lohse, J. Petersen, Stephan Urban, Maura Dandri |