Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation

No specific drugs are currently available against hepatitis delta virus (HDV), a defective virus leading to the most severe form of chronic viral hepatitis in man. The lack of convenient HDV infection models has hampered the development of effective therapeutics. In this study, naïve and hepatitis...

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Bibliographic Details

Main Authors:	Lütgehetmann, Marc (Author) , Urban, Stephan (Author)
Format:	Article (Journal)
Language:	English
Published:	2012
In:	Hepatology Year: 2011, Volume: 55, Issue: 3, Pages: 685-694
ISSN:	1527-3350
DOI:	10.1002/hep.24758
Online Access:	Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1002/hep.24758 Verlag, kostenfrei, Volltext: https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.24758
Author Notes:	Marc Lütgehetmann, Lida V. Mancke, Tassilo Volz, Martina Helbig, Lena Allweiss, Till Bornscheuer, Joerg M. Pollok, Ansgar W. Lohse, J. Petersen, Stephan Urban, Maura Dandri