Forebrain-specific, conditional silencing of Staufen2 alters synaptic plasticity, learning, and memory in rats
Dendritic messenger RNA (mRNA) localization and subsequent local translation in dendrites critically contributes to synaptic plasticity and learning and memory. Little is known, however, about the contribution of RNA-binding proteins (RBPs) to these processes in vivo.
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
17 November 2017
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| In: |
Genome biology
Year: 2017, Volume: 18 |
| ISSN: | 1474-760X |
| DOI: | 10.1186/s13059-017-1350-8 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13059-017-1350-8 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13059-017-1350-8 
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| Author Notes: | Stefan M. Berger, Iván Fernández-Lamo, Kai Schönig, Sandra M. Fernández Moya, Janina Ehses, Rico Schieweck, Stefano Clementi, Thomas Enkel, Sascha Grothe, Oliver von Bohlen und Halbach, Inmaculada Segura, José María Delgado-García, Agnès Gruart, Michael A. Kiebler and Dusan Bartsch |
| Summary: | Dendritic messenger RNA (mRNA) localization and subsequent local translation in dendrites critically contributes to synaptic plasticity and learning and memory. Little is known, however, about the contribution of RNA-binding proteins (RBPs) to these processes in vivo. |
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| Item Description: | Gesehen am 12.06.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1474-760X |
| DOI: | 10.1186/s13059-017-1350-8 |