Interaction between experiment, modeling and simulation of spatial aspects in the JAK2/STAT5 signaling pathway

In this article, we describe how two different approaches, mathematical modeling and quantitative measurements, can be combined to gain new insights on one of the most extensively studied signal transduction pathways, the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pat...

Full description

Bibliographic Details

Main Authors:	Friedmann, Elfriede (Author) , Cuveland, Rebecca de (Author) , Rannacher, Rolf (Author)
Format:	Chapter/Article Conference Paper
Language:	English
Published:	2013
In:	Model Based Parameter Estimation Year: 2012, Pages: 124-143
DOI:	10.1007/978-3-642-30367-8_5
Subjects:	Konferenzschrift
Online Access:	Verlag, Volltext: http://dx.doi.org/10.1007/978-3-642-30367-8_5 Verlag, Volltext: https://link.springer.com/chapter/10.1007/978-3-642-30367-8_5
Author Notes:	Elfriede Friedmann, Andrea C. Pfeifer, Rebecca Neumann, Ursula Klingmüller and Rolf Rannacher