Improvement of auditory hallucinations and reduction of primary auditory area's activation following TMS

Background In the present case study, improvement of auditory hallucinations following transcranial magnetic stimulation (TMS) therapy was investigated with respect to activation changes of the auditory cortices. Methods Using functional magnetic resonance imaging (fMRI), activation of the auditory...

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Main Authors: Giesel, Frederik L. (Author) , Hempel, Albrecht (Author) , Kress, Kai (Author) , Essig, Marco (Author) , Schröder, Johannes (Author)
Format: Article (Journal)
Language:English
Published: 2012
In: European journal of radiology
Year: 2011, Volume: 81, Issue: 6, Pages: 1273-1275
ISSN:1872-7727
DOI:10.1016/j.ejrad.2011.03.002
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.ejrad.2011.03.002
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0720048X11002531
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Author Notes:Frederik L. Giesel, Amit Mehndiratta, Albrecht Hempel, Eckhard Hempel, Kai R. Kress, Marco Essig, Johannes Schröder

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520 |a Background In the present case study, improvement of auditory hallucinations following transcranial magnetic stimulation (TMS) therapy was investigated with respect to activation changes of the auditory cortices. Methods Using functional magnetic resonance imaging (fMRI), activation of the auditory cortices was assessed prior to and after a 4-week TMS series of the left superior temporal gyrus in a schizophrenic patient with medication-resistant auditory hallucinations. Results Hallucinations decreased slightly after the third and profoundly after the fourth week of TMS. Activation in the primary auditory area decreased, whereas activation in the operculum and insula remained stable. Conclusions Combination of TMS and repetitive fMRI is promising to elucidate the physiological changes induced by TMS. 
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