Time course of adiponectin and its relationship to psychological aspects in patients with anorexia nervosa during inpatient treatment
Objective The protein hormone adiponectin promotes metabolic and psychological health. The aim of the study was to track changes in adiponectin levels in response to weight gain and to assess associations between adiponectin and psychological aspects in patients with anorexia nervosa (AN). Methods T...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
December 20, 2017
|
| In: |
PLOS ONE
Year: 2017, Jahrgang: 12, Heft: 12 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0189500 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1371/journal.pone.0189500 Verlag, kostenfrei, Volltext: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189500 
|
| Verfasserangaben: | Magdalena Buckert, Esther Stroe-Kunold, Hans-Christoph Friederich, Daniela Wesche, Christiane Walter, Stefan Kopf, Joe J. Simon, Wolfgang Herzog, Beate Wild |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 157641826X | ||
| 003 | DE-627 | ||
| 005 | 20210815150916.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180615s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1371/journal.pone.0189500 |2 doi | |
| 035 | |a (DE-627)157641826X | ||
| 035 | |a (DE-576)50641826X | ||
| 035 | |a (DE-599)BSZ50641826X | ||
| 035 | |a (OCoLC)1264002025 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Buckert, Magdalena |d 1984- |e VerfasserIn |0 (DE-588)104942381X |0 (DE-627)781928710 |0 (DE-576)403399793 |4 aut | |
| 245 | 1 | 0 | |a Time course of adiponectin and its relationship to psychological aspects in patients with anorexia nervosa during inpatient treatment |c Magdalena Buckert, Esther Stroe-Kunold, Hans-Christoph Friederich, Daniela Wesche, Christiane Walter, Stefan Kopf, Joe J. Simon, Wolfgang Herzog, Beate Wild |
| 264 | 1 | |c December 20, 2017 | |
| 300 | |a 13 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 15.06.2018 | ||
| 520 | |a Objective The protein hormone adiponectin promotes metabolic and psychological health. The aim of the study was to track changes in adiponectin levels in response to weight gain and to assess associations between adiponectin and psychological aspects in patients with anorexia nervosa (AN). Methods To investigate if adiponectin levels depend on AN severity, data were assessed from 11 inpatients with a very low body mass index (BMI) and a high chronicity (high severity group; HSS), and nine with less severe symptoms (LSS). During the course of treatment, serum adiponectin concentrations were assessed on a weekly basis along with BMI. Psychological variables (i.e., depression, anxiety, stress, and AN-specific symptoms) were obtained by means of electronic diaries. Longitudinal regressions and correlations were calculated to evaluate the temporal course of adiponectin and its relationship with psychological self-ratings. Results At the beginning adiponectin was not increased in HSS patients (p = .56), and only marginally elevated in LSS patients (p = 0.07) compared with controls. In HSS patients, adiponectin increased along with BMI during the first treatment phase (i.e., when the BMI of patients was below 16 kg/m2) and thereafter decreased with further weight gain. In LSS patients, adiponectin was not associated with BMI increase. Furthermore, adiponectin was strongly negatively correlated with psychological self-ratings when the BMI of patients was above 16 kg/m2, i.e., higher levels of adiponectin were related to lower ratings of depression, anxiety, and AN-specific symptoms. Discussion The study connects previous varying results by indicating that the course of adiponectin is dependent on BMI and symptom severity. Similarly, associations of adiponectin and psychological health depended on BMI. | ||
| 650 | 4 | |a Adiponectin | |
| 650 | 4 | |a Anorexia nervosa | |
| 650 | 4 | |a Anxiety | |
| 650 | 4 | |a Depression | |
| 650 | 4 | |a Eating | |
| 650 | 4 | |a Inpatients | |
| 650 | 4 | |a Psychological stress | |
| 650 | 4 | |a Psychometrics | |
| 700 | 1 | |a Stroe-Kunold, Esther |d 1979- |e VerfasserIn |0 (DE-588)141476141 |0 (DE-627)627804055 |0 (DE-576)32404867X |4 aut | |
| 700 | 1 | |a Wesche, Daniela |d 1984- |e VerfasserIn |0 (DE-588)1075563232 |0 (DE-627)83349063X |0 (DE-576)443655243 |4 aut | |
| 700 | 1 | |a Hellwig-Walter, Christiane |d 1984- |e VerfasserIn |0 (DE-588)1050037472 |0 (DE-627)783228791 |0 (DE-576)400074311 |4 aut | |
| 700 | 1 | |a Kopf, Stefan |d 1978- |e VerfasserIn |0 (DE-588)1013047516 |0 (DE-627)663343453 |0 (DE-576)346399025 |4 aut | |
| 700 | 1 | |a Simon, Joe J. |d 1981- |e VerfasserIn |0 (DE-588)141634650 |0 (DE-627)630398887 |0 (DE-576)32506413X |4 aut | |
| 700 | 1 | |a Herzog, Wolfgang |d 1953- |e VerfasserIn |0 (DE-588)1028064535 |0 (DE-627)730257452 |0 (DE-576)375551816 |4 aut | |
| 700 | 1 | |a Wild, Beate |d 1968- |e VerfasserIn |0 (DE-588)133928047 |0 (DE-627)558737684 |0 (DE-576)300198280 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t PLOS ONE |d San Francisco, California, US : PLOS, 2006 |g 12(2017,12) Artikel-Nummer e0189500, 13 Seiten |h Online-Ressource |w (DE-627)523574592 |w (DE-600)2267670-3 |w (DE-576)281331979 |x 1932-6203 |7 nnas |a Time course of adiponectin and its relationship to psychological aspects in patients with anorexia nervosa during inpatient treatment |
| 773 | 1 | 8 | |g volume:12 |g year:2017 |g number:12 |g extent:13 |a Time course of adiponectin and its relationship to psychological aspects in patients with anorexia nervosa during inpatient treatment |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1371/journal.pone.0189500 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189500 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180615 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 133928047 |a Wild, Beate |m 133928047:Wild, Beate |d 910000 |d 910100 |d 50000 |e 910000PW133928047 |e 910100PW133928047 |e 50000PW133928047 |k 0/910000/ |k 1/910000/910100/ |k 0/50000/ |p 9 |y j | ||
| 998 | |g 1028064535 |a Herzog, Wolfgang |m 1028064535:Herzog, Wolfgang |d 910000 |d 910100 |d 50000 |e 910000PH1028064535 |e 910100PH1028064535 |e 50000PH1028064535 |k 0/910000/ |k 1/910000/910100/ |k 0/50000/ |p 8 | ||
| 998 | |g 141634650 |a Simon, Joe J. |m 141634650:Simon, Joe J. |d 910000 |d 910700 |e 910000PS141634650 |e 910700PS141634650 |k 0/910000/ |k 1/910000/910700/ |p 7 | ||
| 998 | |g 1013047516 |a Kopf, Stefan |m 1013047516:Kopf, Stefan |d 910000 |d 910100 |e 910000PK1013047516 |e 910100PK1013047516 |k 0/910000/ |k 1/910000/910100/ |p 6 | ||
| 998 | |g 1050037472 |a Hellwig-Walter, Christiane |m 1050037472:Hellwig-Walter, Christiane |d 910000 |d 910600 |e 910000PH1050037472 |e 910600PH1050037472 |k 0/910000/ |k 1/910000/910600/ |p 5 | ||
| 998 | |g 1075563232 |a Wesche, Daniela |m 1075563232:Wesche, Daniela |d 910000 |d 910700 |e 910000PW1075563232 |e 910700PW1075563232 |k 0/910000/ |k 1/910000/910700/ |p 4 | ||
| 998 | |g 141476141 |a Stroe-Kunold, Esther |m 141476141:Stroe-Kunold, Esther |p 2 | ||
| 998 | |g 104942381X |a Buckert, Magdalena |m 104942381X:Buckert, Magdalena |d 910000 |d 910600 |e 910000PB104942381X |e 910600PB104942381X |k 0/910000/ |k 1/910000/910600/ |p 1 |x j | ||
| 999 | |a KXP-PPN157641826X |e 3012763155 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"role":"aut","given":"Magdalena","display":"Buckert, Magdalena","family":"Buckert"},{"role":"aut","given":"Esther","family":"Stroe-Kunold","display":"Stroe-Kunold, Esther"},{"display":"Wesche, Daniela","family":"Wesche","given":"Daniela","role":"aut"},{"role":"aut","given":"Christiane","display":"Hellwig-Walter, Christiane","family":"Hellwig-Walter"},{"display":"Kopf, Stefan","family":"Kopf","role":"aut","given":"Stefan"},{"given":"Joe J.","role":"aut","family":"Simon","display":"Simon, Joe J."},{"given":"Wolfgang","role":"aut","display":"Herzog, Wolfgang","family":"Herzog"},{"display":"Wild, Beate","family":"Wild","role":"aut","given":"Beate"}],"language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"title_sort":"Time course of adiponectin and its relationship to psychological aspects in patients with anorexia nervosa during inpatient treatment","title":"Time course of adiponectin and its relationship to psychological aspects in patients with anorexia nervosa during inpatient treatment"}],"origin":[{"dateIssuedKey":"2017","dateIssuedDisp":"December 20, 2017"}],"note":["Gesehen am 15.06.2018"],"id":{"doi":["10.1371/journal.pone.0189500"],"eki":["157641826X"]},"recId":"157641826X","relHost":[{"corporate":[{"role":"isb","display":"Public Library of Science"}],"part":{"year":"2017","extent":"13","text":"12(2017,12) Artikel-Nummer e0189500, 13 Seiten","issue":"12","volume":"12"},"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Time course of adiponectin and its relationship to psychological aspects in patients with anorexia nervosa during inpatient treatmentPLOS ONE","title":[{"title_sort":"PLOS ONE","title":"PLOS ONE"}],"origin":[{"publisherPlace":"San Francisco, California, US ; Lawrence, Kan.","dateIssuedDisp":"2006-","dateIssuedKey":"2006","publisher":"PLOS ; PLoS"}],"note":["Schreibweise des Titels bis 2012: PLoS ONE","Gesehen am 20.03.19"],"pubHistory":["1.2006 -"],"id":{"eki":["523574592"],"zdb":["2267670-3"],"issn":["1932-6203"]},"physDesc":[{"extent":"Online-Ressource"}],"name":{"displayForm":["Public Library of Science"]},"recId":"523574592"}],"physDesc":[{"extent":"13 S."}],"name":{"displayForm":["Magdalena Buckert, Esther Stroe-Kunold, Hans-Christoph Friederich, Daniela Wesche, Christiane Walter, Stefan Kopf, Joe J. Simon, Wolfgang Herzog, Beate Wild"]}} | ||
| SRT | |a BUCKERTMAGTIMECOURSE2020 | ||