Initial Molecular Response at 3 Months May Predict Both Response and Event-Free Survival at 24 Months in Imatinib-Resistant or -Intolerant Patients With Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase Treated With Nilotinib

Purpose The association between initial molecular response and longer-term outcomes with nilotinib was examined. Patients and Methods Patients with imatinib-resistant or -intolerant chronic myeloid leukemia in chronic phase from the phase II nilotinib registration study with available postbaseline...

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Bibliographic Details
Main Authors: Branford, Susan (Author) , Müller, Martin Christian (Author)
Format: Article (Journal)
Language:English
Published: 2012
In: Journal of clinical oncology
Year: 2012, Volume: 30, Issue: 35, Pages: 4323-4329
ISSN:1527-7755
DOI:10.1200/JCO.2011.40.5217
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1200/JCO.2011.40.5217
Verlag, kostenfrei, Volltext: http://ascopubs.org/doi/10.1200/JCO.2011.40.5217
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Author Notes:Susan Branford, Dong-Wook Kim, Simona Soverini, Ariful Haque, Yaping Shou, Richard C. Woodman, Hagop M. Kantarjian, Giovanni Martinelli, Jerald P. Radich, Giuseppe Saglio, Andreas Hochhaus, Timothy P. Hughes, and Martin C. Müller