Frequent AKT1E17K mutations in skull base meningiomas are associated with mTOR and ERK1/2 activation and reduced time to tumor recurrence

AbstractBackground. Skull base meningiomas are considered to be difficult for surgical treatment. We wondered whether genetic alterations recently identified

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Bibliographische Detailangaben
Hauptverfasser: Yesilöz, Ümmügülsüm (VerfasserIn) , Kirches, Elmar (VerfasserIn) , Hartmann, Christian (VerfasserIn) , Scholz, Johannes (VerfasserIn) , Kropf, Siegfried (VerfasserIn) , Sahm, Felix (VerfasserIn) , Nakamura, Makoto (VerfasserIn) , Mawrin, Christian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2017
In: Neuro-Oncology
Year: 2017, Jahrgang: 19, Heft: 8, Pages: 1088-1096
ISSN:1523-5866
DOI:10.1093/neuonc/nox018
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1093/neuonc/nox018
Verlag, Volltext: https://academic.oup.com/neuro-oncology/article/19/8/1088/3800501
Volltext
Verfasserangaben:Ümmügülsüm Yesilöz, Elmar Kirches, Christian Hartmann, Johannes Scholz, Siegfried Kropf, Felix Sahm, Makoto Nakamura, and Christian Mawrin

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