Frequent AKT1E17K mutations in skull base meningiomas are associated with mTOR and ERK1/2 activation and reduced time to tumor recurrence
AbstractBackground. Skull base meningiomas are considered to be difficult for surgical treatment. We wondered whether genetic alterations recently identified
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| In: |
Neuro-Oncology
Year: 2017, Jahrgang: 19, Heft: 8, Pages: 1088-1096 |
| ISSN: | 1523-5866 |
| DOI: | 10.1093/neuonc/nox018 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1093/neuonc/nox018 Verlag, Volltext: https://academic.oup.com/neuro-oncology/article/19/8/1088/3800501 |
| Verfasserangaben: | Ümmügülsüm Yesilöz, Elmar Kirches, Christian Hartmann, Johannes Scholz, Siegfried Kropf, Felix Sahm, Makoto Nakamura, and Christian Mawrin |
| Zusammenfassung: | AbstractBackground. Skull base meningiomas are considered to be difficult for surgical treatment. We wondered whether genetic alterations recently identified |
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| Beschreibung: | Published: 06 May 2017 Gesehen am 27.06.2018 Im Titel ist "E17K" hochgestellt |
| Beschreibung: | Online Resource |
| ISSN: | 1523-5866 |
| DOI: | 10.1093/neuonc/nox018 |