Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease
Hepatic fat accumulation and changes in lipid composition are hallmarks of nonalcoholic fatty liver disease (NAFLD). As an experimental approach for treatment of NAFLD, we synthesized the bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE). Previous work demonstr...
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| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2012
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| In: |
Hepatology
Year: 2011, Volume: 55, Issue: 5, Pages: 1369-1378 |
| ISSN: | 1527-3350 |
| DOI: | 10.1002/hep.25531 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1002/hep.25531 Verlag, Volltext: https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.25531 |
| Author Notes: | Anita Pathil, Jan Mueller, Arne Warth, Walee Chamulitrat, and Wolfgang Stremmel |