Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease

Hepatic fat accumulation and changes in lipid composition are hallmarks of nonalcoholic fatty liver disease (NAFLD). As an experimental approach for treatment of NAFLD, we synthesized the bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE). Previous work demonstr...

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Bibliographic Details
Main Authors: Pathil-Warth, Anita (Author) , Müller, Jan (Author) , Warth, Arne (Author) , Chamulitrat, Walee (Author) , Stremmel, Wolfgang (Author)
Format: Article (Journal)
Language:English
Published: 2012
In: Hepatology
Year: 2011, Volume: 55, Issue: 5, Pages: 1369-1378
ISSN:1527-3350
DOI:10.1002/hep.25531
Online Access:Verlag, Volltext: http://dx.doi.org/10.1002/hep.25531
Verlag, Volltext: https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.25531
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Author Notes:Anita Pathil, Jan Mueller, Arne Warth, Walee Chamulitrat, and Wolfgang Stremmel