The podocyte's response to stress: the enigma of foot process effacement

Progressive loss of podocytes is the most frequent cause accounting for end-stage renal failure. Podocytes are complex, terminally differentiated cells incapable of replicating. Thus lost podocytes cannot be replaced by proliferation of neighboring undamaged cells. Moreover, podocytes occupy a uniqu...

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Bibliographic Details
Main Author: Kriz, Wilhelm (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: American journal of physiology. Renal physiology
Year: 2013, Volume: 304, Issue: 4, Pages: F333-F347
ISSN:1522-1466
DOI:10.1152/ajprenal.00478.2012
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1152/ajprenal.00478.2012
Verlag, kostenfrei, Volltext: https://www.physiology.org/doi/abs/10.1152/ajprenal.00478.2012
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Author Notes:Wilhelm Kriz, Isao Shirato, Michio Nagata, Michel LeHir, and Kevin V. Lemley