The validity of self-rated psychotic symptoms in depressed inpatients

Background: Self-ratings of psychotic experiences might be biased by depressive symptoms. Method: Data from a large naturalistic multicentre trial on depressed inpatients (n=488) who were assessed on a biweekly basis until discharge were analyzed. Self-rated psychotic symptoms as assessed with the 9...

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Main Authors: Seemüller, Florian (Author) , Kronmüller, Klaus-Thomas (Author)
Format: Article (Journal)
Language:English
Published: 2012
In: European psychiatry
Year: 2011, Volume: 27, Issue: 7, Pages: 547-552
ISSN:1778-3585
DOI:10.1016/j.eurpsy.2011.01.004
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.eurpsy.2011.01.004
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0924933811000071
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Author Notes:F. Seemüller, M. Riedel, M. Obermeier, R. Schennach-Wolff, I. Spellmann, S. Meyer, M. Bauer, M. Adli, K. Kronmüller, M. Ising, P. Brieger, G. Laux, W. Bender, I. Heuser, J. Zeiler, W. Gaebel, H.-J. Möller

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520 |a Background: Self-ratings of psychotic experiences might be biased by depressive symptoms. Method: Data from a large naturalistic multicentre trial on depressed inpatients (n=488) who were assessed on a biweekly basis until discharge were analyzed. Self-rated psychotic symptoms as assessed with the 90-Item Symptom Checklist (SCL-90) were correlated with the SCL-90 total score, the SCL-90 depression score, the Beck Depression Inventory (BDI), the Hamilton Depression Rating Scale 21 item (HAMD-21) total score, the Montgomery Åsberg Depression Rating Scale (MADRS) total score and the clinician-rated paranoid-hallucinatory score of the Association for Methodology and Documentation in Psychiatry (AMDP) scale. Results: At discharge the SCL-90 psychosis score correlated highest with the SCL-90 depression score (0.78, P<0.001) and with the BDI total score (0.64, P<0.001). Moderate correlations were found for the MADRS (0.34, P<0.001), HAMD (0.37, P<0.001) and AMDP depression score (0.33, P<0.001). Only a weak correlation was found between the SCL-90 psychosis score and the AMDP paranoid-hallucinatory syndrome score (0.15, P<0.001). Linear regression showed that change in self-rated psychotic symptoms over the treatment course was best explained by a change in the SCL-90 depression score (P<0.001). The change in clinician-rated AMDP paranoid-hallucinatory score had lesser influence (P=0.02). Conclusions: In depressed patients self-rated psychotic symptoms correlate poorly with clinician-rated psychotic symptoms. Caution is warranted when interpreting results from epidemiological surveys using self-rated psychotic symptom questionnaires as indicators of psychotic symptoms. Depressive symptoms which are highly prevalent in the general population might influence such self-ratings. 
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