Correlation of CT angiographic pulmonary artery obstruction scores with right ventricular dysfunction and clinical outcome in patients with acute pulmonary embolism

OBJECTIVE: To correlate CTA pulmonary artery obstruction scores (OS) with right ventricular dysfunction (RVD) and clinical outcome in patients with acute pulmonary embolism (PE). MATERIALS AND METHODS: In a prospective study of 50 patients (66 ± 12.9 years) with PE pulmonary artery OS (Qanadli, Mast...

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Hauptverfasser: Apfaltrer, Paul (VerfasserIn) , Henzler, Thomas (VerfasserIn) , Meyer, Mathias (VerfasserIn) , Röger, Susanne (VerfasserIn) , Haghi, Dariusch (VerfasserIn) , Grüttner, Joachim (VerfasserIn) , Süselbeck, Tim (VerfasserIn) , Schönberg, Stefan (VerfasserIn) , Fink, Christian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2012
In: European journal of radiology
Year: 2011, Jahrgang: 81, Heft: 10, Pages: 2867-2871
ISSN:1872-7727
DOI:10.1016/j.ejrad.2011.08.014
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/j.ejrad.2011.08.014
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Verfasserangaben:P. Apfaltrer, T. Henzler, M. Meyer, S. Roeger, D. Haghi, J. Gruettner, T. Süselbeck, R. B. Wilson, U. J. Schoepf, S. O. Schoenberg, C. Fink

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245 1 0 |a Correlation of CT angiographic pulmonary artery obstruction scores with right ventricular dysfunction and clinical outcome in patients with acute pulmonary embolism  |c P. Apfaltrer, T. Henzler, M. Meyer, S. Roeger, D. Haghi, J. Gruettner, T. Süselbeck, R. B. Wilson, U. J. Schoepf, S. O. Schoenberg, C. Fink 
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520 |a OBJECTIVE: To correlate CTA pulmonary artery obstruction scores (OS) with right ventricular dysfunction (RVD) and clinical outcome in patients with acute pulmonary embolism (PE). MATERIALS AND METHODS: In a prospective study of 50 patients (66 ± 12.9 years) with PE pulmonary artery OS (Qanadli, Mastora, and Mastora central) were assessed by two radiologists. To assess RVD all patients underwent echocardiography within 24h. Furthermore, RVD on CT was assessed by calculating the right ventricular/left ventricular (RV/LV) diameter ratios on transverse (RV/LVtrans) and four-chamber views (RV/LV4ch) as well as the RV/LV volume ratio (RV/LVvol). OS were correlated with RVD and the occurrence of adverse clinical outcomes (defined as death, need for intensive care treatment, or cardiac insufficiency ≥ NYHA III). RESULTS: Mean Mastora, Qanadli, and Mastora central OS were 26.4 ± 17.7, 12.6 ± 9.9 and 7.5 ± 9, respectively. Echocardiography demonstrated moderate and severe RVD in 10 and 5 patients, respectively. Patients with moderate and severe RVD showed significantly higher Mastora central scores than patients without RVD (14 ± 10.8 vs. 5.9 ± 7.8 [p=0.05]; 17.6 ± 13.2 vs. 5.9 ± 7.8 [p=0.038]). A relevant correlation (i.e. r ≥ 0.6) between OS and CT parameters for RVD were only found for the Mastora score and the Mastora central score (RV/LV4ch: r=0.61 and 0.68, RV/LVvol: r=0.61 and 0.6). 18 patients experienced an adverse clinical outcome. None of the OS differed significantly between patients with and without adverse clinical outcome. CONCLUSION: Pulmonary artery obstruction scores can differentiate between patients with and without RVD. However, in this study, obstruction scores were not correlated to adverse clinical outcome. 
534 |c 2011 
650 4 |a Acute Disease 
650 4 |a Aged 
650 4 |a Angiography 
650 4 |a Female 
650 4 |a Germany 
650 4 |a Humans 
650 4 |a Male 
650 4 |a Prognosis 
650 4 |a Pulmonary Artery 
650 4 |a Pulmonary Embolism 
650 4 |a Reproducibility of Results 
650 4 |a Sensitivity and Specificity 
650 4 |a Severity of Illness Index 
650 4 |a Survival Analysis 
650 4 |a Survival Rate 
650 4 |a Tomography, X-Ray Computed 
650 4 |a Ventricular Dysfunction, Right 
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