Buchumschlag

Implant and midterm outcomes of the subcutaneous implantable cardioverter-defibrillator registry: the EFFORTLESS study

Background: The subcutaneous implantable cardioverter-defibrillator (S-ICD) was developed to defibrillate ventricular arrhythmias, avoiding drawbacks of transvenous leads. The global EFFORTLESS S-ICD (Evaluation oF FactORs ImpacTing CLinical Outcome and Cost EffectiveneSS of the S-ICD) registry is c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Boersma, Lucas (VerfasserIn) , Kuschyk, Jürgen (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2017
In: Journal of the American College of Cardiology
Year: 2017, Jahrgang: 70, Heft: 7, Pages: 830-841
ISSN:1558-3597
DOI:10.1016/j.jacc.2017.06.040
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/j.jacc.2017.06.040
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0735109717379287
Volltext
Verfasserangaben:Lucas Boersma, MD, PhD, Craig Barr, MD, Reinoud Knops, MD, Dominic Theuns, PhD, Lars Eckardt, MD, Petr Neuzil, MD, PhD, Marcoen Scholten, MD, PhD, Margaret Hood, MBCHB, Juergen Kuschyk, MD, Paul Jones, MS, Elizabeth Duffy, MS, Michael Husby, MS, MPH, Kenneth Stein, MD, Pier D. Lambiase, MD, PhD, on behalf of the EFFORTLESS Investigator Group

MARC

LEADER 00000caa a2200000 c 4500
001 1577148789
003 DE-627
005 20240316100448.0
007 cr uuu---uuuuu
008 180702s2017 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.jacc.2017.06.040  |2 doi 
035 |a (DE-627)1577148789 
035 |a (DE-576)507148789 
035 |a (DE-599)BSZ507148789 
035 |a (OCoLC)1341013092 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Boersma, Lucas  |d 1965-  |e VerfasserIn  |0 (DE-588)1161958797  |0 (DE-627)1025469917  |0 (DE-576)507037170  |4 aut 
245 1 0 |a Implant and midterm outcomes of the subcutaneous implantable cardioverter-defibrillator registry  |b the EFFORTLESS study  |c Lucas Boersma, MD, PhD, Craig Barr, MD, Reinoud Knops, MD, Dominic Theuns, PhD, Lars Eckardt, MD, Petr Neuzil, MD, PhD, Marcoen Scholten, MD, PhD, Margaret Hood, MBCHB, Juergen Kuschyk, MD, Paul Jones, MS, Elizabeth Duffy, MS, Michael Husby, MS, MPH, Kenneth Stein, MD, Pier D. Lambiase, MD, PhD, on behalf of the EFFORTLESS Investigator Group 
264 1 |c 2017 
300 |a 12 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Available online 7 August 2017 
500 |a Gesehen am 02.07.2018 
520 |a Background: The subcutaneous implantable cardioverter-defibrillator (S-ICD) was developed to defibrillate ventricular arrhythmias, avoiding drawbacks of transvenous leads. The global EFFORTLESS S-ICD (Evaluation oF FactORs ImpacTing CLinical Outcome and Cost EffectiveneSS of the S-ICD) registry is collecting outcomes in 985 patients during a 5-year follow-up. Objectives: The primary goal of the EFFORTLESS registry is to determine the safety of the S-ICD by evaluating complications and inappropriate shock rate. Methods: This is the first report on the full patient cohort and study endpoints with follow-up ≥1 year. The predefined endpoints are 30- and 360-day complications, and shocks for atrial fibrillation or supraventricular tachycardia. Results: Patients were followed for 3.1 ± 1.5 years and 82 completed the study protocol 5-year visit. Average age was 48 years, 28% were women, ejection fraction was 43 ± 18%, and 65% had a primary prevention indication. The S-ICD system and procedure complication rate was 4.1% at 30 days and 8.4% at 360 days. The 1-year complication rate trended toward improvement from the first to last quartile of enrollment (11.3% [quartile 1]) to 7.8% [quartile 2], 6.6% [quartile 3], and 7.4% [quartile 4]; quartile 1 vs. quartiles 2 to 4; p = 0.06). Few device extractions occurred due to need for antitachycardia (n = 5), or biventricular (n = 4) or bradycardia pacing (n = 1). Inappropriate shocks occurred in 8.1% at 1 year and 11.7% after 3.1 years. At implant, 99.5% of patients had a successful conversion of induced ventricular tachycardia or ventricular fibrillation. The 1- and 5-year rates of appropriate shock were 5.8% and 13.5%, respectively. Conversion success for discrete spontaneous episodes was 97.4% overall. Conclusions: This registry demonstrates that the S-ICD fulfills predefined endpoints for safety and efficacy. Midterm performance rates on complications, inappropriate shocks, and conversion efficacy were comparable to rates observed in transvenous implantable cardioverter-defibrillator studies. 
650 4 |a appropriate therapy 
650 4 |a inappropriate therapy 
650 4 |a leadless 
650 4 |a primary prevention 
650 4 |a secondary prevention 
650 4 |a ventricular arrhythmias 
700 1 |a Kuschyk, Jürgen  |d 1968-  |e VerfasserIn  |0 (DE-588)122441850  |0 (DE-627)081944993  |0 (DE-576)293272212  |4 aut 
773 0 8 |i Enthalten in  |a American College of Cardiology  |t Journal of the American College of Cardiology  |d New York, NY : Elsevier, 1983  |g 70(2017), 7, Seite 830-841  |h Online-Ressource  |w (DE-627)266884717  |w (DE-600)1468327-1  |w (DE-576)099603837  |x 1558-3597  |7 nnas 
773 1 8 |g volume:70  |g year:2017  |g number:7  |g pages:830-841  |g extent:12  |a Implant and midterm outcomes of the subcutaneous implantable cardioverter-defibrillator registry the EFFORTLESS study 
856 4 0 |u http://dx.doi.org/10.1016/j.jacc.2017.06.040  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u http://www.sciencedirect.com/science/article/pii/S0735109717379287  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20180702 
993 |a Article 
994 |a 2017 
998 |g 122441850  |a Kuschyk, Jürgen  |m 122441850:Kuschyk, Jürgen  |d 60000  |e 60000PK122441850  |k 0/60000/  |p 9 
999 |a KXP-PPN1577148789  |e 301544381X 
BIB |a Y 
SER |a journal 
JSO |a {"name":{"displayForm":["Lucas Boersma, MD, PhD, Craig Barr, MD, Reinoud Knops, MD, Dominic Theuns, PhD, Lars Eckardt, MD, Petr Neuzil, MD, PhD, Marcoen Scholten, MD, PhD, Margaret Hood, MBCHB, Juergen Kuschyk, MD, Paul Jones, MS, Elizabeth Duffy, MS, Michael Husby, MS, MPH, Kenneth Stein, MD, Pier D. Lambiase, MD, PhD, on behalf of the EFFORTLESS Investigator Group"]},"note":["Available online 7 August 2017","Gesehen am 02.07.2018"],"recId":"1577148789","person":[{"role":"aut","display":"Boersma, Lucas","family":"Boersma","given":"Lucas"},{"role":"aut","given":"Jürgen","display":"Kuschyk, Jürgen","family":"Kuschyk"}],"physDesc":[{"extent":"12 S."}],"title":[{"title_sort":"Implant and midterm outcomes of the subcutaneous implantable cardioverter-defibrillator registry","subtitle":"the EFFORTLESS study","title":"Implant and midterm outcomes of the subcutaneous implantable cardioverter-defibrillator registry"}],"relHost":[{"type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"id":{"issn":["1558-3597"],"zdb":["1468327-1"],"eki":["266884717"]},"corporate":[{"role":"aut","display":"American College of Cardiology"}],"note":["Gesehen am 13.11.25","Ungezählte Beil.: Supplement"],"pubHistory":["1.1983 -"],"recId":"266884717","disp":"American College of CardiologyJournal of the American College of Cardiology","title":[{"subtitle":"JACC","title":"Journal of the American College of Cardiology","title_sort":"Journal of the American College of Cardiology"}],"physDesc":[{"extent":"Online-Ressource"}],"titleAlt":[{"title":"JACC"}],"part":{"year":"2017","extent":"12","issue":"7","volume":"70","pages":"830-841","text":"70(2017), 7, Seite 830-841"},"origin":[{"publisherPlace":"New York, NY ; New York, NY","dateIssuedDisp":"1983-","dateIssuedKey":"1983","publisher":"Elsevier ; American College of Cardiology"}]}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"eki":["1577148789"],"doi":["10.1016/j.jacc.2017.06.040"]},"language":["eng"],"origin":[{"dateIssuedDisp":"2017","dateIssuedKey":"2017"}]} 
SRT |a BOERSMALUCIMPLANTAND2017 

Ähnliche Einträge