Can prognostic factors be used to direct therapy in chronic lymphocytic leukemia?

Chronic lymphocytic leukemia (CLL) shows a heterogeneous clinical course, which can be explained in part by prognostic factors. Most patients do not need treatment at the time of first diagnosis. The identification of prognostic factors is of major interest if strategies can be devised to treat pati...

Full description

Saved in:
Bibliographic Details
Main Authors: Sellner, Leopold (Author) , Dietrich, Sascha (Author) , Dreger, Peter (Author) , Glimm, Hanno (Author) , Zenz, Thorsten (Author)
Format: Article (Journal)
Language:English
Published: 12 January 2012
In: Current hematologic malignancy reports
Year: 2012, Volume: 7, Issue: 1, Pages: 3-12
ISSN:1558-822X
DOI:10.1007/s11899-011-0110-1
Online Access:Verlag, Volltext: http://dx.doi.org/10.1007/s11899-011-0110-1
Verlag, Volltext: https://link.springer.com/article/10.1007/s11899-011-0110-1
Get full text
Author Notes:Leopold Sellner, Sascha Dietrich, Peter Dreger, Hanno Glimm, Thorsten Zenz

MARC

LEADER 00000caa a2200000 c 4500
001 1577289722
003 DE-627
005 20220814183812.0
007 cr uuu---uuuuu
008 180704s2012 xx |||||o 00| ||eng c
024 7 |a 10.1007/s11899-011-0110-1  |2 doi 
035 |a (DE-627)1577289722 
035 |a (DE-576)507289722 
035 |a (DE-599)BSZ507289722 
035 |a (OCoLC)1341013330 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Sellner, Leopold  |d 1984-  |e VerfasserIn  |0 (DE-588)143493825  |0 (DE-627)646576704  |0 (DE-576)337362963  |4 aut 
245 1 0 |a Can prognostic factors be used to direct therapy in chronic lymphocytic leukemia?  |c Leopold Sellner, Sascha Dietrich, Peter Dreger, Hanno Glimm, Thorsten Zenz 
264 1 |c 12 January 2012 
300 |a 10 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 04.07.2018 
520 |a Chronic lymphocytic leukemia (CLL) shows a heterogeneous clinical course, which can be explained in part by prognostic factors. Most patients do not need treatment at the time of first diagnosis. The identification of prognostic factors is of major interest if strategies can be devised to treat patients according to their individual risk profile or biological subgroup. Currently, in spite of a wealth of prognostic factors, individualized treatment approaches in different genetic or risk groups are the exemption in CLL. This review summarizes the most important prognostic and predictive factors in CLL, with particular emphasis on factors affecting treatment decisions in clinical trials and routine practice. 
700 1 |a Dietrich, Sascha  |d 1979-  |e VerfasserIn  |0 (DE-588)136406300  |0 (DE-627)694354635  |0 (DE-576)301003408  |4 aut 
700 1 |a Dreger, Peter  |e VerfasserIn  |0 (DE-588)1028891881  |0 (DE-627)732699894  |0 (DE-576)376320966  |4 aut 
700 1 |a Glimm, Hanno  |d 1967-  |e VerfasserIn  |0 (DE-588)113880677  |0 (DE-627)51985120X  |0 (DE-576)289777879  |4 aut 
700 1 |a Zenz, Thorsten  |d 1970-  |e VerfasserIn  |0 (DE-588)114963738  |0 (DE-627)577184202  |0 (DE-576)180278266  |4 aut 
773 0 8 |i Enthalten in  |t Current hematologic malignancy reports  |d Philadelphia, Pa. : Current Science, 2006  |g 7(2012), 1, Seite 3-12  |h Online-Ressource  |w (DE-627)534675549  |w (DE-600)2374151-X  |w (DE-576)306834618  |x 1558-822X  |7 nnas  |a Can prognostic factors be used to direct therapy in chronic lymphocytic leukemia? 
773 1 8 |g volume:7  |g year:2012  |g number:1  |g pages:3-12  |g extent:10  |a Can prognostic factors be used to direct therapy in chronic lymphocytic leukemia? 
856 4 0 |u http://dx.doi.org/10.1007/s11899-011-0110-1  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u https://link.springer.com/article/10.1007/s11899-011-0110-1  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20180704 
993 |a Article 
994 |a 2012 
998 |g 114963738  |a Zenz, Thorsten  |m 114963738:Zenz, Thorsten  |d 910000  |d 950000  |d 950950  |e 910000PZ114963738  |e 950000PZ114963738  |e 950950PZ114963738  |k 0/910000/  |k 1/910000/950000/  |k 2/910000/950000/950950/  |p 5  |y j 
998 |g 113880677  |a Glimm, Hanno  |m 113880677:Glimm, Hanno  |d 140000  |e 140000PG113880677  |k 0/140000/  |p 4 
998 |g 1028891881  |a Dreger, Peter  |m 1028891881:Dreger, Peter  |d 910000  |d 910100  |e 910000PD1028891881  |e 910100PD1028891881  |k 0/910000/  |k 1/910000/910100/  |p 3 
998 |g 136406300  |a Dietrich, Sascha  |m 136406300:Dietrich, Sascha  |d 910000  |d 910100  |e 910000PD136406300  |e 910100PD136406300  |k 0/910000/  |k 1/910000/910100/  |p 2 
998 |g 143493825  |a Sellner, Leopold  |m 143493825:Sellner, Leopold  |d 910000  |d 910100  |e 910000PS143493825  |e 910100PS143493825  |k 0/910000/  |k 1/910000/910100/  |p 1  |x j 
999 |a KXP-PPN1577289722  |e 3016127059 
BIB |a Y 
SER |a journal 
JSO |a {"relHost":[{"title":[{"title_sort":"Current hematologic malignancy reports","title":"Current hematologic malignancy reports"}],"note":["Gesehen am 27.02.14"],"type":{"bibl":"periodical","media":"Online-Ressource"},"origin":[{"dateIssuedDisp":"2006-","publisherPlace":"Philadelphia, Pa.","publisher":"Current Science","dateIssuedKey":"2006"}],"pubHistory":["1.2006 -"],"id":{"zdb":["2374151-X"],"eki":["534675549"],"issn":["1558-822X"]},"disp":"Can prognostic factors be used to direct therapy in chronic lymphocytic leukemia?Current hematologic malignancy reports","part":{"issue":"1","pages":"3-12","volume":"7","extent":"10","year":"2012","text":"7(2012), 1, Seite 3-12"},"language":["eng"],"physDesc":[{"extent":"Online-Ressource"}],"recId":"534675549"}],"note":["Gesehen am 04.07.2018"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"name":{"displayForm":["Leopold Sellner, Sascha Dietrich, Peter Dreger, Hanno Glimm, Thorsten Zenz"]},"id":{"eki":["1577289722"],"doi":["10.1007/s11899-011-0110-1"]},"recId":"1577289722","physDesc":[{"extent":"10 S."}],"language":["eng"],"person":[{"given":"Leopold","family":"Sellner","role":"aut","display":"Sellner, Leopold"},{"family":"Dietrich","role":"aut","display":"Dietrich, Sascha","given":"Sascha"},{"given":"Peter","display":"Dreger, Peter","role":"aut","family":"Dreger"},{"family":"Glimm","display":"Glimm, Hanno","role":"aut","given":"Hanno"},{"given":"Thorsten","family":"Zenz","role":"aut","display":"Zenz, Thorsten"}],"title":[{"title":"Can prognostic factors be used to direct therapy in chronic lymphocytic leukemia?","title_sort":"Can prognostic factors be used to direct therapy in chronic lymphocytic leukemia?"}],"origin":[{"dateIssuedKey":"2012","dateIssuedDisp":"12 January 2012"}]} 
SRT |a SELLNERLEOCANPROGNOS1220