Soluble TREM-1 as a diagnostic and prognostic biomarker in patients with septic shock: an observational clinical study
Objectives: The impact of TREM-1-mediated inflammation was investigated in different inflammatory settings.Methods: Secondary analyses of an observational clinical pilot study, including 60 patients with septic shock, 30 postoperative controls and 30 healthy volunteers.Results: Plasma levels of sTRE...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| In: |
Biomarkers
Year: 2017, Jahrgang: 22, Heft: 1, Pages: 63-69 |
| ISSN: | 1366-5804 |
| DOI: | 10.1080/1354750X.2016.1204005 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1080/1354750X.2016.1204005 Verlag, Volltext: https://doi.org/10.1080/1354750X.2016.1204005 
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| Verfasserangaben: | Thorsten Brenner, Florian Uhle, Thomas Fleming, Matthias Wieland, Thomas Schmoch, Felix Schmitt, Karsten Schmidt, Aleksandar R. Zivkovic, Thomas Bruckner, Markus A. Weigand & Stefan Hofer |
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| 245 | 1 | 0 | |a Soluble TREM-1 as a diagnostic and prognostic biomarker in patients with septic shock |b an observational clinical study |c Thorsten Brenner, Florian Uhle, Thomas Fleming, Matthias Wieland, Thomas Schmoch, Felix Schmitt, Karsten Schmidt, Aleksandar R. Zivkovic, Thomas Bruckner, Markus A. Weigand & Stefan Hofer |
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| 520 | |a Objectives: The impact of TREM-1-mediated inflammation was investigated in different inflammatory settings.Methods: Secondary analyses of an observational clinical pilot study, including 60 patients with septic shock, 30 postoperative controls and 30 healthy volunteers.Results: Plasma levels of sTREM-1 were found to identify patients with septic shock more effectively than procalcitonin and C-reactive protein. Moreover, sTREM-1 was identified to be an early predictor for survival in patients with septic shock.Conclusion: Due to its diagnostic as well as prognostic value in sepsis syndrome, implementation of sTREM-1 measurements in routine diagnostics should be taken into account. | ||
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