Clinical characteristics indicating adenomyosis at the time of hysterectomy: a retrospective study in 291 patients

PurposeTo better characterize adenomyosis as a disease entity.MethodsWe retrospectively reviewed the medical records of women undergoing hysterectomy with a histologic diagnosis of adenomyosis, adenomyosis and leiomyomas, and leiomyomas alone.ResultsThe study included 291 women: 38 with adenomyosis...

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Hauptverfasser: Ţăran, Florin-Andrei (VerfasserIn) , Wallwiener, Markus (VerfasserIn) , Krämer, Bernhard (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2012
In: Archives of gynecology and obstetrics
Year: 2011, Jahrgang: 285, Heft: 6, Pages: 1571-1576
ISSN:1432-0711
DOI:10.1007/s00404-011-2180-7
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1007/s00404-011-2180-7
Verlag, Volltext: https://link.springer.com/article/10.1007/s00404-011-2180-7
Volltext
Verfasserangaben:F. Andrei Taran, Markus Wallwiener, Drita Kabashi, Ralf Rothmund, Katharina Rall, Bernhard Kraemer, Sara Y. Brucker

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520 |a PurposeTo better characterize adenomyosis as a disease entity.MethodsWe retrospectively reviewed the medical records of women undergoing hysterectomy with a histologic diagnosis of adenomyosis, adenomyosis and leiomyomas, and leiomyomas alone.ResultsThe study included 291 women: 38 with adenomyosis alone, 56 with adenomyosis and leiomyomas, and 197 with leiomyomas alone. In univariate analysis, women with adenomyosis were younger (p = 0.018) and had lower uterine weights (p < 0.001) and more disease-specific symptoms (p = 0.008). In multinomial logistic regression analysis, a lower uterine weight (OR 0.99, CI 95% 0.99-1.0), pelvic pain (OR 4.8, CI 95% 1.5-15.2), a history of smoking (OR 2.6, CI 95% 1.1-6.5) and at least one delivery (OR 4.3, CI 95% 1.5-12.3) were associated with a greater likelihood of having adenomyosis but not leiomyomas alone.ConclusionsWomen undergoing hysterectomy with adenomyosis alone have different clinical characteristics from women with adenomyosis and leiomyomas and from those with only leiomyomas. 
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