Systemische Amyloidosen
Amyloidoses are rare protein folding disorders, in which proteins are deposited as insoluble fibrillar aggregates due to a conformational change. This can occur in a local or systemic form. Systemic amyloidoses are life-threatening complications of monoclonal gammopathy, chronic inflammatory disease...
Gespeichert in:
| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Deutsch |
| Veröffentlicht: |
2012
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| In: |
Der Internist
Year: 2011, Jahrgang: 53, Heft: 1, Pages: 51-64 |
| ISSN: | 1432-1289 |
| DOI: | 10.1007/s00108-011-2952-y |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1007/s00108-011-2952-y Verlag, Volltext: https://link.springer.com/article/10.1007/s00108-011-2952-y 
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| Verfasserangaben: | S. Schönland, N. Blank, A.V. Kristen, J. Beimler, T. Ganten, U. Hegenbart |
| Zusammenfassung: | Amyloidoses are rare protein folding disorders, in which proteins are deposited as insoluble fibrillar aggregates due to a conformational change. This can occur in a local or systemic form. Systemic amyloidoses are life-threatening complications of monoclonal gammopathy, chronic inflammatory diseases or within hereditary diseases. The causative treatment of amyloidosis is the reduction of the amyloid precursor protein by chemotherapy, anti-inflammatory treatment, or liver transplantation. Early diagnosis of the disease is essential in order to effectively treat patients and avoid further deterioration of organ functions. |
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| Beschreibung: | Gesehen am 11.07.2018 Online publiziert: 27. Oktober 2011 |
| Beschreibung: | Online Resource |
| ISSN: | 1432-1289 |
| DOI: | 10.1007/s00108-011-2952-y |