Eukaryotic ribosome assembly, transport and quality control
Eukaryotic ribosome synthesis is a complex, energy-consuming process that takes place across the nucleolus, nucleoplasm and cytoplasm and requires more than 200 conserved assembly factors. Here, we discuss mechanisms by which the ribosome assembly and nucleocytoplasmic transport machineries collabor...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
07 September 2017
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| In: |
Nature structural & molecular biology
Year: 2017, Jahrgang: 24, Heft: 9, Pages: 689-699 |
| ISSN: | 1545-9985 |
| DOI: | 10.1038/nsmb.3454 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1038/nsmb.3454 Verlag, Volltext: https://www.nature.com/articles/nsmb.3454 
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| Verfasserangaben: | Cohue Peña, Ed Hurt & Vikram Govind Panse |
| Zusammenfassung: | Eukaryotic ribosome synthesis is a complex, energy-consuming process that takes place across the nucleolus, nucleoplasm and cytoplasm and requires more than 200 conserved assembly factors. Here, we discuss mechanisms by which the ribosome assembly and nucleocytoplasmic transport machineries collaborate to produce functional ribosomes. We also highlight recent cryo-EM studies that provided unprecedented snapshots of ribosomes during assembly and quality control. |
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| Beschreibung: | Gesehen am 11.07.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1545-9985 |
| DOI: | 10.1038/nsmb.3454 |