Biomaterials and computation: a strategic alliance to investigate emergent responses of neural cells
Topographical and chemical cues drive migration, outgrowth and regeneration of neurons in different and crucial biological conditions. In the natural extracellular matrix, their influences are so closely coupled that they result in complex cellular responses. As a consequence, engineered biomaterial...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
16 Feb 2017
|
| In: |
Biomaterials science
Year: 2017, Jahrgang: 5, Heft: 4, Pages: 648-657 |
| ISSN: | 2047-4849 |
| DOI: | 10.1039/C6BM00871B |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1039/C6BM00871B Verlag, Volltext: https://pubs.rsc.org/en/content/articlelanding/2017/bm/c6bm00871b 
|
| Verfasserangaben: | Pier Nicola Sergi and Elisabetta Ada Cavalcanti-Adam |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1577560086 | ||
| 003 | DE-627 | ||
| 005 | 20230426230642.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180712s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1039/C6BM00871B |2 doi | |
| 035 | |a (DE-627)1577560086 | ||
| 035 | |a (DE-576)507560086 | ||
| 035 | |a (DE-599)BSZ507560086 | ||
| 035 | |a (OCoLC)1341013789 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Sergi, Pier Nicola |e VerfasserIn |0 (DE-588)1162650192 |0 (DE-627)102725795X |0 (DE-576)507559207 |4 aut | |
| 245 | 1 | 0 | |a Biomaterials and computation |b a strategic alliance to investigate emergent responses of neural cells |c Pier Nicola Sergi and Elisabetta Ada Cavalcanti-Adam |
| 264 | 1 | |c 16 Feb 2017 | |
| 300 | |a 10 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a First published on 16 Feb 2017 | ||
| 500 | |a Gesehen am 12.07.2018 | ||
| 520 | |a Topographical and chemical cues drive migration, outgrowth and regeneration of neurons in different and crucial biological conditions. In the natural extracellular matrix, their influences are so closely coupled that they result in complex cellular responses. As a consequence, engineered biomaterials are widely used to simplify in vitro conditions, disentangling intricate in vivo behaviours, and narrowing the investigation on particular emergent responses. Nevertheless, how topographical and chemical cues affect the emergent response of neural cells is still unclear, thus in silico models are used as additional tools to reproduce and investigate the interactions between cells and engineered biomaterials. This work aims at presenting the synergistic use of biomaterials-based experiments and computation as a strategic way to promote the discovering of complex neural responses as well as to allow the interactions between cells and biomaterials to be quantitatively investigated, fostering a rational design of experiments. | ||
| 700 | 1 | |a Cavalcanti-Adam, Elisabetta A. |d 1972- |e VerfasserIn |0 (DE-588)1059179458 |0 (DE-627)798132256 |0 (DE-576)189133511 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Biomaterials science |d Cambridge : Royal Soc. of Chemistry, 2013 |g 5(2017), 4, Seite 648-657 |h Online-Ressource |w (DE-627)731887018 |w (DE-600)2693928-9 |w (DE-576)377476188 |x 2047-4849 |7 nnas |a Biomaterials and computation a strategic alliance to investigate emergent responses of neural cells |
| 773 | 1 | 8 | |g volume:5 |g year:2017 |g number:4 |g pages:648-657 |g extent:10 |a Biomaterials and computation a strategic alliance to investigate emergent responses of neural cells |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1039/C6BM00871B |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://pubs.rsc.org/en/content/articlelanding/2017/bm/c6bm00871b |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180712 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 1059179458 |a Cavalcanti-Adam, Elisabetta A. |m 1059179458:Cavalcanti-Adam, Elisabetta A. |d 120000 |e 120000PC1059179458 |k 0/120000/ |p 2 |y j | ||
| 999 | |a KXP-PPN1577560086 |e 3017489256 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"title":[{"title_sort":"Biomaterials and computation","subtitle":"a strategic alliance to investigate emergent responses of neural cells","title":"Biomaterials and computation"}],"person":[{"display":"Sergi, Pier Nicola","roleDisplay":"VerfasserIn","role":"aut","family":"Sergi","given":"Pier Nicola"},{"given":"Elisabetta A.","family":"Cavalcanti-Adam","role":"aut","roleDisplay":"VerfasserIn","display":"Cavalcanti-Adam, Elisabetta A."}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["First published on 16 Feb 2017","Gesehen am 12.07.2018"],"recId":"1577560086","language":["eng"],"origin":[{"dateIssuedDisp":"16 Feb 2017","dateIssuedKey":"2017"}],"id":{"eki":["1577560086"],"doi":["10.1039/C6BM00871B"]},"name":{"displayForm":["Pier Nicola Sergi and Elisabetta Ada Cavalcanti-Adam"]},"physDesc":[{"extent":"10 S."}],"relHost":[{"id":{"issn":["2047-4849"],"zdb":["2693928-9"],"eki":["731887018"]},"origin":[{"dateIssuedDisp":"2013-","dateIssuedKey":"2013","publisher":"Royal Soc. of Chemistry","publisherPlace":"Cambridge"}],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title":"Biomaterials science","title_sort":"Biomaterials science"}],"recId":"731887018","language":["eng"],"note":["Fortsetzung der Druck-Ausgabe","Gesehen am 15.05.2017"],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Biomaterials and computation a strategic alliance to investigate emergent responses of neural cellsBiomaterials science","part":{"pages":"648-657","issue":"4","year":"2017","extent":"10","text":"5(2017), 4, Seite 648-657","volume":"5"},"pubHistory":["1.2013 -"]}]} | ||
| SRT | |a SERGIPIERNBIOMATERIA1620 | ||