Dose reduction techniques in coronary calcium scoring: the effect of iterative reconstruction combined with low tube voltage on calcium scores in a thoracic phantom

Objectives: To define a dose-reduced coronary calcium CT protocol that provides similar calcium score values as a conventional 120kVp protocol. Methods: A thorax phantom containing 100 calcifications was scanned with the reference protocol (120kVp, 90 ref mAs, FBP) and 30 dose-reduced protocols (70-...

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Hauptverfasser: Vonder, Marleen (VerfasserIn) , Meyer, Mathias (VerfasserIn) , Henzler, Thomas (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 4 June 2017
In: European journal of radiology
Year: 2017, Jahrgang: 93, Pages: 229-235
ISSN:1872-7727
DOI:10.1016/j.ejrad.2017.06.001
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/j.ejrad.2017.06.001
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0720048X17302334
Volltext
Verfasserangaben:Marleen Vonder, Gert Jan Pelgrim, Mathias Meyer, Thomas Henzler, Matthijs Oudkerk, Rozemarijn Vliegenthart

MARC

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520 |a Objectives: To define a dose-reduced coronary calcium CT protocol that provides similar calcium score values as a conventional 120kVp protocol. Methods: A thorax phantom containing 100 calcifications was scanned with the reference protocol (120kVp, 90 ref mAs, FBP) and 30 dose-reduced protocols (70-110kVp, 90 ref mAs, FBP and iterative reconstruction (IR) levels 1-5) with 3rd generation dual-source CT. For protocols that yielded similar detectability and calcium scores as the reference protocol, additional scans were acquired at reduced ref mAs. Kendall’s τb and independent-samples-median test were used to determine trends and differences in contrast/signal-to-noise ratio (CNR and SNR), dose and calcium scores. Results: The detectability and calcium scores decreased at increasing IR levels (τb<−0.825, p<0.001) and increasing tube voltage (τb<−0.679, p<0.001). For 90kVp-IR3 and 100kVp-IR1, similar detectability and calcium score was found compared to the reference protocol (p>0.206). For these protocols, lower tube currents did not affect the detectability and Agatston score (p>0.206), while CNR and SNR were similar/higher compared to the reference protocol (0.008<p<0.206). Dose reduction was 60.6% (90kVp-IR3) and 43.6% (100kVp-IR1). Conclusions: The protocol of 90kVp-IR3 and 100kVp-IR1 yielded similar calcium detectability, Agatston score and image quality as the reference protocol, with dose reduction up to 60.6%. 
650 4 |a Coronary artery disease 
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