Short-course radiation plus temozolomide in elderly patients with glioblastoma

Glioblastoma is a fatal illness that is associated with a median survival of less than 2 years. Population studies of glioblastoma have shown that survival declines with increasing age,1,2 and the incidence of glioblastoma is increasing, especially among the elderly.3 Older patients have been underr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Perry, James R. (VerfasserIn) , Wick, Antje (VerfasserIn) , Wick, Wolfgang (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: March 16, 2017
In: The New England journal of medicine
Year: 2017, Jahrgang: 376, Heft: 11, Pages: 1027-1037
ISSN:1533-4406
DOI:10.1056/NEJMoa1611977
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1056/NEJMoa1611977
Verlag, Volltext: https://doi.org/10.1056/NEJMoa1611977
Volltext
Verfasserangaben:James R. Perry, Normand Laperriere, Christopher J. O’Callaghan, Alba A. Brandes, Johan Menten, Claire Phillips, Michael Fay, Ryo Nishikawa, J. Gregory Cairncross, Wilson Roa, David Osoba, John P. Rossiter, Arjun Sahgal, Hal Hirte, Florence Laigle-Donadey, Enrico Franceschi, Olivier Chinot, Vassilis Golfinopoulos, Laura Fariselli, Antje Wick, Loic Feuvret, Michael Back, Michael Tills, Chad Winch, Brigitta G. Baumert, Wolfgang Wick, Keyue Ding, and Warren P. Mason

MARC

LEADER 00000caa a2200000 c 4500
001 1577760468
003 DE-627
005 20230426230711.0
007 cr uuu---uuuuu
008 180719s2017 xx |||||o 00| ||eng c
024 7 |a 10.1056/NEJMoa1611977  |2 doi 
035 |a (DE-627)1577760468 
035 |a (DE-576)507760468 
035 |a (DE-599)BSZ507760468 
035 |a (OCoLC)1341014069 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Perry, James R.  |e VerfasserIn  |0 (DE-588)1163042560  |0 (DE-627)1027286348  |0 (DE-576)507760352  |4 aut 
245 1 0 |a Short-course radiation plus temozolomide in elderly patients with glioblastoma  |c James R. Perry, Normand Laperriere, Christopher J. O’Callaghan, Alba A. Brandes, Johan Menten, Claire Phillips, Michael Fay, Ryo Nishikawa, J. Gregory Cairncross, Wilson Roa, David Osoba, John P. Rossiter, Arjun Sahgal, Hal Hirte, Florence Laigle-Donadey, Enrico Franceschi, Olivier Chinot, Vassilis Golfinopoulos, Laura Fariselli, Antje Wick, Loic Feuvret, Michael Back, Michael Tills, Chad Winch, Brigitta G. Baumert, Wolfgang Wick, Keyue Ding, and Warren P. Mason 
264 1 |c March 16, 2017 
300 |a 11 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 19.07.2018 
520 |a Glioblastoma is a fatal illness that is associated with a median survival of less than 2 years. Population studies of glioblastoma have shown that survival declines with increasing age,1,2 and the incidence of glioblastoma is increasing, especially among the elderly.3 Older patients have been underrepresented in most randomized trials, in which the average age of participants is approximately 55 years, as compared with the population-based median for patients with glioblastoma of 65 years of age.2 In 2005, a phase 3 trial of radiotherapy alone (60 Gy over a period of 6 weeks) versus radiotherapy plus temozolomide showed longer survival . . . 
700 1 |a Wick, Antje  |d 1972-  |e VerfasserIn  |0 (DE-588)122759869  |0 (DE-627)706032101  |0 (DE-576)293409609  |4 aut 
700 1 |a Wick, Wolfgang  |d 1970-  |e VerfasserIn  |0 (DE-588)120297736  |0 (DE-627)080586929  |0 (DE-576)186221320  |4 aut 
773 0 8 |i Enthalten in  |t The New England journal of medicine  |d Waltham, Mass. : MMS, 1928  |g 376(2017), 11, Seite 1027-1037  |h Online-Ressource  |w (DE-627)266889484  |w (DE-600)1468837-2  |w (DE-576)075962454  |x 1533-4406  |7 nnas  |a Short-course radiation plus temozolomide in elderly patients with glioblastoma 
773 1 8 |g volume:376  |g year:2017  |g number:11  |g pages:1027-1037  |g extent:11  |a Short-course radiation plus temozolomide in elderly patients with glioblastoma 
856 4 0 |u http://dx.doi.org/10.1056/NEJMoa1611977  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u https://doi.org/10.1056/NEJMoa1611977  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20180719 
993 |a Article 
994 |a 2017 
998 |g 120297736  |a Wick, Wolfgang  |m 120297736:Wick, Wolfgang  |d 910000  |d 911100  |e 910000PW120297736  |e 911100PW120297736  |k 0/910000/  |k 1/910000/911100/  |p 26 
998 |g 122759869  |a Wick, Antje  |m 122759869:Wick, Antje  |d 910000  |d 911100  |e 910000PW122759869  |e 911100PW122759869  |k 0/910000/  |k 1/910000/911100/  |p 20 
999 |a KXP-PPN1577760468  |e 3018328000 
BIB |a Y 
SER |a journal 
JSO |a {"relHost":[{"recId":"266889484","origin":[{"dateIssuedKey":"1928","publisher":"MMS ; MMS","publisherPlace":"Waltham, Mass. ; Boston, Mass.","dateIssuedDisp":"1928-"}],"disp":"Short-course radiation plus temozolomide in elderly patients with glioblastomaThe New England journal of medicine","language":["eng"],"title":[{"title_sort":"New England journal of medicine","subtitle":"NEJM","title":"The New England journal of medicine"}],"name":{"displayForm":["Massachusetts Medical Society"]},"titleAlt":[{"title":"NEJM"}],"id":{"eki":["266889484"],"zdb":["1468837-2"],"issn":["1533-4406"]},"physDesc":[{"extent":"Online-Ressource"}],"note":["Gesehen am 04.08.25"],"part":{"text":"376(2017), 11, Seite 1027-1037","volume":"376","extent":"11","year":"2017","pages":"1027-1037","issue":"11"},"type":{"media":"Online-Ressource","bibl":"periodical"},"corporate":[{"role":"isb","display":"Massachusetts Medical Society","roleDisplay":"Herausgebendes Organ"}],"pubHistory":["198.1928 -"]}],"note":["Gesehen am 19.07.2018"],"id":{"eki":["1577760468"],"doi":["10.1056/NEJMoa1611977"]},"physDesc":[{"extent":"11 S."}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"name":{"displayForm":["James R. Perry, Normand Laperriere, Christopher J. O’Callaghan, Alba A. Brandes, Johan Menten, Claire Phillips, Michael Fay, Ryo Nishikawa, J. Gregory Cairncross, Wilson Roa, David Osoba, John P. Rossiter, Arjun Sahgal, Hal Hirte, Florence Laigle-Donadey, Enrico Franceschi, Olivier Chinot, Vassilis Golfinopoulos, Laura Fariselli, Antje Wick, Loic Feuvret, Michael Back, Michael Tills, Chad Winch, Brigitta G. Baumert, Wolfgang Wick, Keyue Ding, and Warren P. Mason"]},"origin":[{"dateIssuedDisp":"March 16, 2017","dateIssuedKey":"2017"}],"recId":"1577760468","language":["eng"],"person":[{"roleDisplay":"VerfasserIn","family":"Perry","display":"Perry, James R.","role":"aut","given":"James R."},{"roleDisplay":"VerfasserIn","family":"Wick","display":"Wick, Antje","role":"aut","given":"Antje"},{"given":"Wolfgang","role":"aut","display":"Wick, Wolfgang","family":"Wick","roleDisplay":"VerfasserIn"}],"title":[{"title_sort":"Short-course radiation plus temozolomide in elderly patients with glioblastoma","title":"Short-course radiation plus temozolomide in elderly patients with glioblastoma"}]} 
SRT |a PERRYJAMESSHORTCOURS1620