Evaluation of particle radiotherapy for the re-irradiation of recurrent intracranial meningioma

With the advance of modern irradiation techniques, the role of radiotherapy (RT) for intracranial meningioma has increased significantly throughout the past years. Despite that tumor’s generally favorable outcome with local control rates of up to 90% after ten years, progression after RT does occur....

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Hauptverfasser: El-Shafie, Rami (VerfasserIn) , Czech, Maja (VerfasserIn) , Eitz, Kerstin Anne (VerfasserIn) , Habermehl, Daniel (VerfasserIn) , Kronsteiner, Dorothea (VerfasserIn) , Rieken, Stefan (VerfasserIn) , Bougatf, Nina (VerfasserIn) , Jäkel, Oliver (VerfasserIn) , Debus, Jürgen (VerfasserIn) , Combs, Stephanie (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 8 May 2018
In: Radiation oncology
Year: 2018, Jahrgang: 13
ISSN:1748-717X
DOI:10.1186/s13014-018-1026-x
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13014-018-1026-x
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-018-1026-x
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Verfasserangaben:Rami A. El Shafie, Maja Czech, Kerstin A. Kessel, Daniel Habermehl, Dorothea Weber, Stefan Rieken, Nina Bougatf, Oliver Jäkel, Jürgen Debus and Stephanie E. Combs
Beschreibung
Zusammenfassung:With the advance of modern irradiation techniques, the role of radiotherapy (RT) for intracranial meningioma has increased significantly throughout the past years. Despite that tumor’s generally favorable outcome with local control rates of up to 90% after ten years, progression after RT does occur. In those cases, re-irradiation is often difficult due to the limited radiation tolerance of the surrounding tissue. The aim of this analysis is to determine the value of particle therapy with its better dose conformity and higher biological efficacy for re-irradiating recurrent intracranial meningioma. It was performed within the framework of the “clinical research group heavy ion therapy” and funded by the German Research Council (DFG, KFO 214).
Beschreibung:Gesehen am 19.07.2018
Beschreibung:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-018-1026-x