Feasibility of spectral shaping for detection and quantification of coronary calcifications in ultra-low dose CT
ObjectivesTo evaluate detectability and quantification of coronary calcifications for CT with a tin filter for spectral shaping.MethodsPhantom inserts with 100 small and 9 large calcifications, and a moving artificial artery with 3 calcifications (speed 0-30 mm/s) were placed in a thorax phantom sim...
Gespeichert in:
| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| In: |
European radiology
Year: 2016, Jahrgang: 27, Heft: 5, Pages: 2047-2054 |
| ISSN: | 1432-1084 |
| DOI: | 10.1007/s00330-016-4507-z |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1007/s00330-016-4507-z Verlag, Volltext: https://link.springer.com/article/10.1007/s00330-016-4507-z 
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| Verfasserangaben: | Marleen Vonder, Gert Jan Pelgrim, Sèvrin E. M. Huijsse, Mathias Meyer, Marcel J. W. Greuter, Thomas Henzler, Thomas G. Flohr, Matthijs Oudkerk, Rozemarijn Vliegenthart |
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| 245 | 1 | 0 | |a Feasibility of spectral shaping for detection and quantification of coronary calcifications in ultra-low dose CT |c Marleen Vonder, Gert Jan Pelgrim, Sèvrin E. M. Huijsse, Mathias Meyer, Marcel J. W. Greuter, Thomas Henzler, Thomas G. Flohr, Matthijs Oudkerk, Rozemarijn Vliegenthart |
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| 520 | |a ObjectivesTo evaluate detectability and quantification of coronary calcifications for CT with a tin filter for spectral shaping.MethodsPhantom inserts with 100 small and 9 large calcifications, and a moving artificial artery with 3 calcifications (speed 0-30 mm/s) were placed in a thorax phantom simulating different patient sizes. The phantom was scanned in high-pitch spiral mode at 100 kVp with tin filter (Sn100 kVp), and at a reference of 120 kVp, with electrocardiographic (ECG) gating. Detectability and quantification of calcifications were analyzed for standard (130 HU) and adapted thresholds.ResultsSn100 kVp yielded lower detectability of calcifications (9 % versus 12 %, p = 0.027) and lower Agatston scores (p < 0.008), irrespective of calcification, patient size and speed. Volume scores of the moving calcifications for Sn100 kVp at speed 10-30 mm/s were lower (p < 0.001), while mass scores were similar (p = 0.131). For Sn100 kVp with adapted threshold of 117 HU, detectability (p = 1.000) and Agatston score (p > 0.206) were similar to 120 kVp. Spectral shaping resulted in median dose reduction of 62.3 % (range 59.0-73.4 %).ConclusionsCoronary calcium scanning with spectral shaping yields lower detectability of calcifications and lower Agatston scores compared to 120 kVp scanning, for which a HU threshold correction should be developed. Key points • Sn100kVp yields lower detectability and lower Agatston scores compared to 120kVp • Adapted HU threshold for Sn100kVp provides Agatston scores comparable to 120kVp • Sn100 kVp considerably reduces dose in calcium scoring versus 120 kVp | ||
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