Chemical basis for alteration of an intraocular lens using a femtosecond laser

The chemical basis for the alteration of the refractive properties of an intraocular lens with a femtosecond laser was investigated. Three different microscope setups have been used for the study: Laser Induced Fluorescence (LIF) microscopy, Raman microscopy and coherent anti-Stokes Raman Scattering...

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Hauptverfasser: Bille, Josef F. (VerfasserIn) , Engelhardt, Johann (VerfasserIn) , Volpp, Hans-Robert (VerfasserIn) , Laghouissa, Abdelmoutalib (VerfasserIn) , Motzkus, Marcus (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 6 Feb 2017
In: Biomedical optics express
Year: 2017, Jahrgang: 8, Heft: 3, Pages: 1390-1404
ISSN:2156-7085
DOI:10.1364/BOE.8.001390
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1364/BOE.8.001390
Verlag, kostenfrei, Volltext: https://www.osapublishing.org/boe/abstract.cfm?uri=boe-8-3-1390
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Verfasserangaben:Josef F. Bille, Johann Engelhardt, Hans-Robert Volpp, Abdelmoutalib Laghouissa, Marcus Motzkus, Zhongxiang Jiang, and Ruth Sahler

MARC

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520 |a The chemical basis for the alteration of the refractive properties of an intraocular lens with a femtosecond laser was investigated. Three different microscope setups have been used for the study: Laser Induced Fluorescence (LIF) microscopy, Raman microscopy and coherent anti-Stokes Raman Scattering (CARS) microscopy. Photo-induced hydrolysis of polymeric material in aqueous media produces two hydrophilic functional groups: acid group and alcohol group. The spectral signatures identify two of the hydrophilic polar molecules as N-phenyl-4-(phenylazo)-benzenamine (C18H15N3) and phenazine-1-carboxylic acid (C13H8N2O2). The change in hydrophilicity results in a negative refractive index change in the laser-treated areas. 
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