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FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve

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Fragile-X-Mental-Retardation-1- (FMR1)-gene is supposed to be a key gene for ovarian reserve and folliculogenesis. It contains in its 5’-UTR a triplet-base-repeat (CGG), that varies between 26 and 34 in general population. CGG-repeat-lengths with 55-200 repeats (pre-mutation = PM) show instable here...

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Main Authors: Rehnitz, Julia (Author) , Alcoba, Diego Duarte (Author) , Dietrich, Jens Erik (Author) , Youness, Berthe (Author) , Hinderhofer, Katrin (Author) , Messmer, Birgitta (Author) , Freis, Alexander (Author) , Strowitzki, Thomas (Author) , Germeyer, Ariane (Author)
Format: Article (Journal)
Language:English
Published: 7 July 2018
In: Reproductive biology and endocrinology
Year: 2018, Volume: 16
ISSN:1477-7827
DOI:10.1186/s12958-018-0383-5
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s12958-018-0383-5
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12958-018-0383-5
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Author Notes:Julia Rehnitz, Diego D. Alcoba, Ilma S. Brum, Jens E. Dietrich, Berthe Youness, Katrin Hinderhofer, Birgitta Messmer, Alexander Freis, Thomas Strowitzki and Ariane Germeyer
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FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve by Rehnitz, Julia (Author) , Alcoba, Diego Duarte (Author) , Brum, Jens E. (Author) , Dietrich, Jens Erik (Author) , Youness, Berthe (Author) , Hinderhofer, Katrin (Author) , Messmer, Birgitta (Author) , Freis, Alexander (Author) , Strowitzki, Thomas (Author) , Germeyer, Ariane (Author) ,

BioMed Central 10. Juli 2018 Universitätsbibliothek Heidelberg 10. Juli 2018

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