Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial

Purpose: We investigated whether bortezomib during induction and maintenance improves survival in newly diagnosed multiple myeloma (MM). Patients and Methods: In all, 827 eligible patients with newly diagnosed symptomatic MM were randomly assigned to receive induction therapy with vincristine, doxor...

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Bibliographic Details
Main Authors: Sonneveld, Pieter (Author) , Bertsch, Uta (Author) , Hose, Dirk (Author) , Jauch, Anna (Author) , Goldschmidt, Hartmut (Author)
Format: Article (Journal)
Language:English
Published: July 16, 2012
In: Journal of clinical oncology
Year: 2012, Volume: 30, Issue: 24, Pages: 2946-2955
ISSN:1527-7755
DOI:10.1200/JCO.2011.39.6820
Online Access:Verlag, Volltext: http://dx.doi.org/10.1200/JCO.2011.39.6820
Verlag, Volltext: http://ascopubs.org/doi/10.1200/JCO.2011.39.6820
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Author Notes:Pieter Sonneveld, Ingo G.H. Schmidt-Wolf, Bronno van der Holt, Laila el Jarari, Uta Bertsch, Hans Salwender, Sonja Zweegman, Edo Vellenga, Annemiek Broyl, Igor W. Blau, Katja C. Weisel, Shulamiet Wittebol, Gerard M.J. Bos, Marian Stevens-Kroef, Christof Scheid, Michael Pfreundschuh, Dirk Hose, Anna Jauch, Helgi van der Velde, Reinier Raymakers, Martijn R. Schaafsma, Marie-Jose Kersten, Marinus van Marwijk-Kooy, Ulrich Duehrsen, Walter Lindemann, Pierre W. Wijermans, Henk M. Lokhorst, and Hartmut M. Goldschmidt