Alterations in the neuroendocrinological stress response to acute psychosocial stress in adolescents engaging in nonsuicidal self-injury

Summary: Objective:To investigate the neuroendocrinological stress response to acute psychosocial stress in a clinical sample of female adolescents engaging in nonsuicidal self-injury (NSSI). Methods: The Trier Social Stress Test (TSST), a standardized psychosocial stress protocol, was performed in...

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Hauptverfasser: Kaess, Michael (VerfasserIn) , Hille, Markus (VerfasserIn) , Parzer, Peter (VerfasserIn) , Maser-Gluth, Christiane (VerfasserIn) , Resch, Franz (VerfasserIn) , Brunner, Romuald (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2012
In: Psychoneuroendocrinology
Year: 2011, Jahrgang: 37, Heft: 1, Pages: 157-161
ISSN:1873-3360
Online-Zugang:Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0306453011001624
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Verfasserangaben:Michael Kaess, Markus Hille, Peter Parzer, Christiane Maser-Gluth, Franz Resch, Romuald Brunner
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Zusammenfassung:Summary: Objective:To investigate the neuroendocrinological stress response to acute psychosocial stress in a clinical sample of female adolescents engaging in nonsuicidal self-injury (NSSI). Methods: The Trier Social Stress Test (TSST), a standardized psychosocial stress protocol, was performed in 14 female patients who engaged in NSSI and 14 healthy control subjects. NSSI was assessed by the Functional Assessment of Self-Mutilation (FASM). Salivary cortisol, heart rate, and affective states, assessed by the Positive and Negative Affect Schedule (PANAS), were measured during the TSST. Results: We found an attenuated cortisol response to acute psychosocial stress in female adolescents with NSSI, whereas no group differences were observed in heart rate and emotional response to the TSST. Conclusions: These findings indicate that the HPA axis is hyporesponsive in adolescents with NSSI. Therefore, reduced secretion of cortisol could play a role in promoting vulnerability of these individuals to acute stress and maladaptive stress responses.
Beschreibung:Available online 15 June 2011
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ISSN:1873-3360