Murine models of diabetic nephropathy
Diabetic nephropathy is the leading cause of end stage renal diseases worldwide. Even though several diabetic animal models exist, not a single one develops renal changes sufficiently reflecting those seen in humans. This review provides an overview on mouse models presenting with various features o...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
08. März 2012
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| In: |
Experimental and clinical endocrinology & diabetes
Year: 2012, Jahrgang: 120, Heft: 4, Pages: 191-193 |
| ISSN: | 1439-3646 |
| DOI: | 10.1055/s-0032-1304569 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1055/s-0032-1304569 Verlag, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0032-1304569 |
| Verfasserangaben: | V. Peters, C.P. Schmitt |
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| 520 | |a Diabetic nephropathy is the leading cause of end stage renal diseases worldwide. Even though several diabetic animal models exist, not a single one develops renal changes sufficiently reflecting those seen in humans. This review provides an overview on mouse models presenting with various features of diabetic nephropathy. The critical analysis and comparison of existing mouse models substantially enhances our understanding of the disease process and should provide a guide for choosing the most suitable mouse model for the investigation of diabetic nephropathy. | ||
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