Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes

The cytoprotective effects of activated protein C (aPC) are well established. In contrast, the receptors and signaling mechanism through which aPC conveys cytoprotection in various cell types remain incompletely defined. Thus, within the renal glomeruli, aPC preserves endothelial cells via a proteas...

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Bibliographische Detailangaben

Hauptverfasser:	Madhusudhan, Thati (VerfasserIn) , Straub, Beate Katharina (VerfasserIn) , Gröne, Elisabeth (VerfasserIn) , Müller-Krebs, Sandra (VerfasserIn) , Schwenger, Vedat (VerfasserIn) , Gröne, Hermann-Josef (VerfasserIn) , Nawroth, Peter Paul (VerfasserIn)
Dokumenttyp:	Article (Journal)
Sprache:	Englisch
Veröffentlicht:	2012
In:	Blood Year: 2012, Jahrgang: 119, Heft: 3, Pages: 874-883
ISSN:	1528-0020
DOI:	10.1182/blood-2011-07-365973
Online-Zugang:	Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1182/blood-2011-07-365973 Verlag, kostenfrei, Volltext: http://www.bloodjournal.org/content/119/3/874
Verfasserangaben:	Thati Madhusudhan, Hongjie Wang, Beate K. Straub, Elisabeth Gröne, Qianxing Zhou, Khurrum Shahzad, Sandra Müller-Krebs, Vedat Schwenger, Bruce Gerlitz, Brian W. Grinnell, John H. Griffin, Jochen Reiser, Hermann-Josef Gröne, Charles T. Esmon, Peter P. Nawroth, and Berend Isermann