Circulating microparticles in patients with benign and malignant ovarian tumors
Background: Microparticles are known to be increased in various malignancies. In this prospective study, microparticle levels were evaluated in patients with benign and malignant ovarian lesions. Patients and Methods: Microparticles from platelets/megakaryocytes, activated platelets and endothelial...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2012
|
| In: |
Anticancer research
Year: 2012, Jahrgang: 32, Heft: 5, Pages: 2009-2014 |
| ISSN: | 1791-7530 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://ar.iiarjournals.org/content/32/5/2009
|
| Verfasserangaben: | A. Rank, S. Liebhardt, J. Zwirner, A. Burges, R. Nieuwland and B. Toth |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1578433525 | ||
| 003 | DE-627 | ||
| 005 | 20220814213517.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180809s2012 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)1578433525 | ||
| 035 | |a (DE-576)508433525 | ||
| 035 | |a (DE-599)BSZ508433525 | ||
| 035 | |a (OCoLC)1341016661 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Rank, Andreas |d 1973- |e VerfasserIn |0 (DE-588)124349978 |0 (DE-627)085804223 |0 (DE-576)186551347 |4 aut | |
| 245 | 1 | 0 | |a Circulating microparticles in patients with benign and malignant ovarian tumors |c A. Rank, S. Liebhardt, J. Zwirner, A. Burges, R. Nieuwland and B. Toth |
| 264 | 1 | |c 2012 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Keine DOI vorhanden | ||
| 500 | |a Gesehen am 09.08.2018 | ||
| 520 | |a Background: Microparticles are known to be increased in various malignancies. In this prospective study, microparticle levels were evaluated in patients with benign and malignant ovarian lesions. Patients and Methods: Microparticles from platelets/megakaryocytes, activated platelets and endothelial cells, tissue factor exposing microparticles and D-dimer values were examined in patients with newly diagnosed ovarian lesions before surgery, and were correlated with tumor histology. Results: Higher counts of CD63-positive microparticles were detected in patients with ovarian cancer [mean=276×106 (range: 64-948)/l; n=12] as compared to patients with benign ovarian tumors [146×106 (45-390)/l; n=21; p=0.014]. D-dimer values were also increased in patients with cancer [860 (180-4500) ng/l versus 280 (170-2720) ng/l; p=0.001]. Conclusion: Elevated levels of CD63-positive microparticles and D-dimer reflect the procoagulant phenotype of these patients. However, for the discrimination between benign and malignant ovarian tumors, measuring preoperative levels of microparticles does not seem to be helpful. | ||
| 650 | 4 | |a D-dimer | |
| 650 | 4 | |a Microparticles | |
| 650 | 4 | |a ovarian cancer | |
| 650 | 4 | |a thrombosis | |
| 700 | 1 | |a Toth, Bettina |d 1971- |e VerfasserIn |0 (DE-588)115537457 |0 (DE-627)691388032 |0 (DE-576)177266228 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Anticancer research |d Kapandriti, Attiki, Greece : International Institute of Anticancer Research, 2004 |g 32(2012), 5, Seite 2009-2014 |h Online-Ressource |w (DE-627)387478493 |w (DE-600)2145376-7 |w (DE-576)358408717 |x 1791-7530 |7 nnas |a Circulating microparticles in patients with benign and malignant ovarian tumors |
| 773 | 1 | 8 | |g volume:32 |g year:2012 |g number:5 |g pages:2009-2014 |g extent:6 |a Circulating microparticles in patients with benign and malignant ovarian tumors |
| 856 | 4 | 0 | |u http://ar.iiarjournals.org/content/32/5/2009 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180809 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 115537457 |a Toth, Bettina |m 115537457:Toth, Bettina |d 910000 |d 910400 |e 910000PT115537457 |e 910400PT115537457 |k 0/910000/ |k 1/910000/910400/ |p 6 |y j | ||
| 999 | |a KXP-PPN1578433525 |e 3020517923 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"id":{"eki":["1578433525"]},"origin":[{"dateIssuedKey":"2012","dateIssuedDisp":"2012"}],"name":{"displayForm":["A. Rank, S. Liebhardt, J. Zwirner, A. Burges, R. Nieuwland and B. Toth"]},"relHost":[{"pubHistory":["Nachgewiesen 24.2004 -"],"part":{"pages":"2009-2014","issue":"5","year":"2012","extent":"6","text":"32(2012), 5, Seite 2009-2014","volume":"32"},"disp":"Circulating microparticles in patients with benign and malignant ovarian tumorsAnticancer research","note":["Gesehen am 26.02.13"],"type":{"bibl":"periodical","media":"Online-Ressource"},"recId":"387478493","language":["eng"],"title":[{"title_sort":"Anticancer research","title":"Anticancer research","subtitle":"international journal of cancer research and treatment"}],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedKey":"2004","publisher":"International Institute of Anticancer Research","dateIssuedDisp":"2004-","publisherPlace":"Kapandriti, Attiki, Greece"}],"id":{"issn":["1791-7530"],"zdb":["2145376-7"],"eki":["387478493"]},"name":{"displayForm":["International Institute of Anticancer Research"]}}],"physDesc":[{"extent":"6 S."}],"title":[{"title":"Circulating microparticles in patients with benign and malignant ovarian tumors","title_sort":"Circulating microparticles in patients with benign and malignant ovarian tumors"}],"person":[{"roleDisplay":"VerfasserIn","display":"Rank, Andreas","role":"aut","family":"Rank","given":"Andreas"},{"given":"Bettina","family":"Toth","role":"aut","roleDisplay":"VerfasserIn","display":"Toth, Bettina"}],"recId":"1578433525","language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Keine DOI vorhanden","Gesehen am 09.08.2018"]} | ||
| SRT | |a RANKANDREACIRCULATIN2012 | ||