Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 gy) and intraoperative radiation therapy (15 gy) in patients with primarily resectable pancreatic cancer - NEOPANC
The current standard treatment, at least in Europe, for patients with primarily resectable tumors, consists of surgery followed by adjuvant chemotherapy. But even in this prognostic favourable group, long term survival is disappointing because of high local and distant failure rates. Postoperative c...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
23 March 2012
|
| In: |
BMC cancer
Year: 2012, Jahrgang: 12 |
| ISSN: | 1471-2407 |
| DOI: | 10.1186/1471-2407-12-112 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/1471-2407-12-112 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/1471-2407-12-112 
|
| Verfasserangaben: | Falk Roeder, Carmen Timke, Ladan Saleh-Ebrahimi, Lutz Schneider, Thilo Hackert, Werner Hartwig, Annette Kopp-Schneider, Frank W. Hensley, Markus W. Buechler, Juergen Debus, Peter E. Huber and Jens Werner |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1578852889 | ||
| 003 | DE-627 | ||
| 005 | 20220814215711.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180814s2012 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1186/1471-2407-12-112 |2 doi | |
| 035 | |a (DE-627)1578852889 | ||
| 035 | |a (DE-576)508852889 | ||
| 035 | |a (DE-599)BSZ508852889 | ||
| 035 | |a (OCoLC)1341016898 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Röder, Falk |d 1973- |e VerfasserIn |0 (DE-588)130040371 |0 (DE-627)488065194 |0 (DE-576)297964550 |4 aut | |
| 245 | 1 | 0 | |a Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 gy) and intraoperative radiation therapy (15 gy) in patients with primarily resectable pancreatic cancer - NEOPANC |c Falk Roeder, Carmen Timke, Ladan Saleh-Ebrahimi, Lutz Schneider, Thilo Hackert, Werner Hartwig, Annette Kopp-Schneider, Frank W. Hensley, Markus W. Buechler, Juergen Debus, Peter E. Huber and Jens Werner |
| 264 | 1 | |c 23 March 2012 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 14.08.2018 | ||
| 520 | |a The current standard treatment, at least in Europe, for patients with primarily resectable tumors, consists of surgery followed by adjuvant chemotherapy. But even in this prognostic favourable group, long term survival is disappointing because of high local and distant failure rates. Postoperative chemoradiation has shown improved local control and overalls survival compared to surgery alone but the value of additional radiation has been questioned in case of adjuvant chemotherapy. However, there remains a strong rationale for the addition of radiation therapy considering the high rates of microscopically incomplete resections after surgery. As postoperative administration of radiation therapy has some general disadvantages, neoadjuvant and intraoperative approaches theoretically offer benefits in terms of dose escalation, reduction of toxicity and patients comfort especially if hypofractionated regimens with highly conformal techniques like intensity-modulated radiation therapy are considered. | ||
| 700 | 1 | |a Timke, Carmen |d 1976- |e VerfasserIn |0 (DE-588)1013171535 |0 (DE-627)704974991 |0 (DE-576)346651840 |4 aut | |
| 700 | 1 | |a Saleh-Ebrahimi, Ladan |d 1978- |e VerfasserIn |0 (DE-588)103369746X |0 (DE-627)742417824 |0 (DE-576)381329526 |4 aut | |
| 700 | 1 | |a Schneider, Lutz |d 1976- |e VerfasserIn |0 (DE-588)124284078 |0 (DE-627)706595483 |0 (DE-576)294101799 |4 aut | |
| 700 | 1 | |a Hackert, Thilo |d 1971- |e VerfasserIn |0 (DE-588)122158512 |0 (DE-627)70579346X |0 (DE-576)182659208 |4 aut | |
| 700 | 1 | |a Hartwig, Werner |d 1970- |e VerfasserIn |0 (DE-588)115574646 |0 (DE-627)077338219 |0 (DE-576)289957494 |4 aut | |
| 700 | 1 | |a Kopp-Schneider, Annette |e VerfasserIn |0 (DE-588)1119160545 |0 (DE-627)872460444 |0 (DE-576)178153206 |4 aut | |
| 700 | 1 | |a Hensley, Frank W. |e VerfasserIn |0 (DE-588)1075059895 |0 (DE-627)832910562 |0 (DE-576)278454070 |4 aut | |
| 700 | 1 | |a Büchler, Markus W. |d 1955- |e VerfasserIn |0 (DE-588)120893339 |0 (DE-627)080952526 |0 (DE-576)292434146 |4 aut | |
| 700 | 1 | |a Debus, Jürgen |d 1964- |e VerfasserIn |0 (DE-588)1022671421 |0 (DE-627)717025780 |0 (DE-576)365774944 |4 aut | |
| 700 | 1 | |a Huber, Peter E. |d 1965- |e VerfasserIn |0 (DE-588)1074678869 |0 (DE-627)832350109 |0 (DE-576)442767803 |4 aut | |
| 700 | 1 | |a Werner, Jens |d 1966- |e VerfasserIn |0 (DE-588)120690764 |0 (DE-627)704926717 |0 (DE-576)292340249 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t BMC cancer |d London : BioMed Central, 2001 |g 12(2012) Artikel-Nummer 112, 8 Seiten |h Online-Ressource |w (DE-627)326643710 |w (DE-600)2041352-X |w (DE-576)107014645 |x 1471-2407 |7 nnas |a Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 gy) and intraoperative radiation therapy (15 gy) in patients with primarily resectable pancreatic cancer - NEOPANC |
| 773 | 1 | 8 | |g volume:12 |g year:2012 |a Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 gy) and intraoperative radiation therapy (15 gy) in patients with primarily resectable pancreatic cancer - NEOPANC |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1186/1471-2407-12-112 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://doi.org/10.1186/1471-2407-12-112 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180814 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 120690764 |a Werner, Jens |m 120690764:Werner, Jens |d 910000 |d 910200 |e 910000PW120690764 |e 910200PW120690764 |k 0/910000/ |k 1/910000/910200/ |p 12 |y j | ||
| 998 | |g 1074678869 |a Huber, Peter E. |m 1074678869:Huber, Peter E. |d 50000 |e 50000PH1074678869 |k 0/50000/ |p 11 | ||
| 998 | |g 1022671421 |a Debus, Jürgen |m 1022671421:Debus, Jürgen |d 910000 |d 911400 |e 910000PD1022671421 |e 911400PD1022671421 |k 0/910000/ |k 1/910000/911400/ |p 10 | ||
| 998 | |g 120893339 |a Büchler, Markus W. |m 120893339:Büchler, Markus W. |d 910000 |d 910200 |e 910000PB120893339 |e 910200PB120893339 |k 0/910000/ |k 1/910000/910200/ |p 9 | ||
| 998 | |g 1075059895 |a Hensley, Frank W. |m 1075059895:Hensley, Frank W. |d 910000 |d 911400 |e 910000PH1075059895 |e 911400PH1075059895 |k 0/910000/ |k 1/910000/911400/ |p 8 | ||
| 998 | |g 1119160545 |a Kopp-Schneider, Annette |m 1119160545:Kopp-Schneider, Annette |d 50000 |e 50000PK1119160545 |k 0/50000/ |p 7 | ||
| 998 | |g 115574646 |a Hartwig, Werner |m 115574646:Hartwig, Werner |d 910000 |d 910200 |e 910000PH115574646 |e 910200PH115574646 |k 0/910000/ |k 1/910000/910200/ |p 6 | ||
| 998 | |g 122158512 |a Hackert, Thilo |m 122158512:Hackert, Thilo |d 910000 |d 910200 |e 910000PH122158512 |e 910200PH122158512 |k 0/910000/ |k 1/910000/910200/ |p 5 | ||
| 998 | |g 124284078 |a Schneider, Lutz |m 124284078:Schneider, Lutz |d 910000 |d 910200 |e 910000PS124284078 |e 910200PS124284078 |k 0/910000/ |k 1/910000/910200/ |p 4 | ||
| 998 | |g 103369746X |a Saleh-Ebrahimi, Ladan |m 103369746X:Saleh-Ebrahimi, Ladan |d 910000 |d 911400 |e 910000PS103369746X |e 911400PS103369746X |k 0/910000/ |k 1/910000/911400/ |p 3 | ||
| 998 | |g 1013171535 |a Timke, Carmen |m 1013171535:Timke, Carmen |d 910000 |d 911400 |e 910000PT1013171535 |e 911400PT1013171535 |k 0/910000/ |k 1/910000/911400/ | ||
| 998 | |g 130040371 |a Röder, Falk |m 130040371:Röder, Falk |d 910000 |d 911400 |e 910000PR130040371 |e 911400PR130040371 |k 0/910000/ |k 1/910000/911400/ |p 1 |x j | ||
| 999 | |a KXP-PPN1578852889 |e 3021148050 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1578852889","note":["Gesehen am 14.08.2018"],"language":["eng"],"title":[{"title_sort":"Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 gy) and intraoperative radiation therapy (15 gy) in patients with primarily resectable pancreatic cancer - NEOPANC","title":"Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 gy) and intraoperative radiation therapy (15 gy) in patients with primarily resectable pancreatic cancer - NEOPANC"}],"id":{"eki":["1578852889"],"doi":["10.1186/1471-2407-12-112"]},"person":[{"roleDisplay":"VerfasserIn","role":"aut","family":"Röder","given":"Falk","display":"Röder, Falk"},{"display":"Timke, Carmen","given":"Carmen","family":"Timke","role":"aut","roleDisplay":"VerfasserIn"},{"role":"aut","roleDisplay":"VerfasserIn","given":"Ladan","family":"Saleh-Ebrahimi","display":"Saleh-Ebrahimi, Ladan"},{"display":"Schneider, Lutz","family":"Schneider","given":"Lutz","roleDisplay":"VerfasserIn","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","given":"Thilo","family":"Hackert","display":"Hackert, Thilo"},{"role":"aut","roleDisplay":"VerfasserIn","given":"Werner","family":"Hartwig","display":"Hartwig, Werner"},{"role":"aut","roleDisplay":"VerfasserIn","given":"Annette","family":"Kopp-Schneider","display":"Kopp-Schneider, Annette"},{"roleDisplay":"VerfasserIn","role":"aut","family":"Hensley","given":"Frank W.","display":"Hensley, Frank W."},{"given":"Markus W.","family":"Büchler","display":"Büchler, Markus W.","role":"aut","roleDisplay":"VerfasserIn"},{"display":"Debus, Jürgen","given":"Jürgen","family":"Debus","role":"aut","roleDisplay":"VerfasserIn"},{"role":"aut","roleDisplay":"VerfasserIn","family":"Huber","given":"Peter E.","display":"Huber, Peter E."},{"display":"Werner, Jens","given":"Jens","family":"Werner","roleDisplay":"VerfasserIn","role":"aut"}],"name":{"displayForm":["Falk Roeder, Carmen Timke, Ladan Saleh-Ebrahimi, Lutz Schneider, Thilo Hackert, Werner Hartwig, Annette Kopp-Schneider, Frank W. Hensley, Markus W. Buechler, Juergen Debus, Peter E. Huber and Jens Werner"]},"origin":[{"dateIssuedKey":"2012","dateIssuedDisp":"23 March 2012"}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"id":{"zdb":["2041352-X"],"issn":["1471-2407"],"eki":["326643710"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 gy) and intraoperative radiation therapy (15 gy) in patients with primarily resectable pancreatic cancer - NEOPANCBMC cancer","origin":[{"dateIssuedDisp":"2001-","dateIssuedKey":"2001","publisherPlace":"London ; Berlin ; Heidelberg","publisher":"BioMed Central ; Springer"}],"note":["Gesehen am 22.05.20"],"recId":"326643710","title":[{"title":"BMC cancer","title_sort":"BMC cancer"}],"pubHistory":["1.2001 -"],"language":["eng"],"part":{"year":"2012","volume":"12","text":"12(2012) Artikel-Nummer 112, 8 Seiten"}}],"type":{"bibl":"article-journal","media":"Online-Ressource"}} | ||
| SRT | |a ROEDERFALKCLINICALPH2320 | ||