Dynamic changes in the transcriptional profile of subventricular zone-derived postnatally born neuroblasts
The subventricular zone (SVZ) of the lateral ventricles is a major neurogenic region in the postnatal mammalian brain. Thousands of neuroblasts are generated daily throughout the life of an animal. Newly born neuroblasts migrate via the rostral migratory stream (RMS) into the olfactory bulb where th...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2013
|
| In: |
Mechanisms of development
Year: 2012, Jahrgang: 130, Heft: 6, Pages: 424-432 |
| ISSN: | 1872-6356 |
| DOI: | 10.1016/j.mod.2012.11.003 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.mod.2012.11.003 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0925477312001141 
|
| Verfasserangaben: | Konstantin Khodosevich, Julieta Alfonso, Hannah Monyer |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1580107729 | ||
| 003 | DE-627 | ||
| 005 | 20220814221528.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180816r20132012xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.mod.2012.11.003 |2 doi | |
| 035 | |a (DE-627)1580107729 | ||
| 035 | |a (DE-576)510107729 | ||
| 035 | |a (DE-599)BSZ510107729 | ||
| 035 | |a (OCoLC)1341017035 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Khodosevich, Konstantin |e VerfasserIn |0 (DE-588)107837970X |0 (DE-627)838447333 |0 (DE-576)451439821 |4 aut | |
| 245 | 1 | 0 | |a Dynamic changes in the transcriptional profile of subventricular zone-derived postnatally born neuroblasts |c Konstantin Khodosevich, Julieta Alfonso, Hannah Monyer |
| 264 | 1 | |c 2013 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Available online 5 December 2012 | ||
| 500 | |a Gesehen am 16.08.2018 | ||
| 520 | |a The subventricular zone (SVZ) of the lateral ventricles is a major neurogenic region in the postnatal mammalian brain. Thousands of neuroblasts are generated daily throughout the life of an animal. Newly born neuroblasts migrate via the rostral migratory stream (RMS) into the olfactory bulb where they mature into distinct neuronal subtypes. Neuroblasts exiting the SVZ retain the ability to proliferate, however, proliferation declines in the course of migration to the olfactory bulb. While migrating in the RMS, neuroblasts receive a plethora of stimuli that modify transcription according to the local microenvironment, and eventually modulate neuroblast migration. In the target area, the olfactory bulb, neuroblasts develop into mature neurons. In this review, we discuss dynamic changes of the transcriptome that occur during the “lifetime” of a neuroblast, thereby governing the activation or inhibition of distinct genes/pathways that are responsible for proliferation, migration and differentiation. | ||
| 534 | |c 2012 | ||
| 650 | 4 | |a Differentiation | |
| 650 | 4 | |a Gene expression | |
| 650 | 4 | |a Migration | |
| 650 | 4 | |a Neuroblasts | |
| 650 | 4 | |a Proliferation | |
| 650 | 4 | |a Subventricular zone | |
| 700 | 1 | |a Alfonso, Julieta |e VerfasserIn |0 (DE-588)1101609478 |0 (DE-627)85978777X |0 (DE-576)469974796 |4 aut | |
| 700 | 1 | |a Monyer, Hannah |d 1957- |e VerfasserIn |0 (DE-588)1012792374 |0 (DE-627)662740416 |0 (DE-576)345945514 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Mechanisms of development |d Shannon : Elsevier, 1990 |g 130(2013), 6, Seite 424-432 |h Online-Ressource |w (DE-627)265784255 |w (DE-600)1466356-9 |w (DE-576)074891057 |x 1872-6356 |7 nnas |a Dynamic changes in the transcriptional profile of subventricular zone-derived postnatally born neuroblasts |
| 773 | 1 | 8 | |g volume:130 |g year:2013 |g number:6 |g pages:424-432 |g extent:9 |a Dynamic changes in the transcriptional profile of subventricular zone-derived postnatally born neuroblasts |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.mod.2012.11.003 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S0925477312001141 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180816 | ||
| 993 | |a Article | ||
| 994 | |a 2013 | ||
| 998 | |g 1012792374 |a Monyer, Hannah |m 1012792374:Monyer, Hannah |d 910000 |d 911100 |e 910000PM1012792374 |e 911100PM1012792374 |k 0/910000/ |k 1/910000/911100/ |p 3 |y j | ||
| 998 | |g 1101609478 |a Alfonso, Julieta |m 1101609478:Alfonso, Julieta |d 910000 |d 911100 |e 910000PA1101609478 |e 911100PA1101609478 |k 0/910000/ |k 1/910000/911100/ |p 2 | ||
| 998 | |g 107837970X |a Khodosevich, Konstantin |m 107837970X:Khodosevich, Konstantin |d 910000 |d 911100 |e 910000PK107837970X |e 911100PK107837970X |k 0/910000/ |k 1/910000/911100/ |p 1 |x j | ||
| 999 | |a KXP-PPN1580107729 |e 302245757X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"title":[{"subtitle":"MOD ; the official journal of the International Society of Developmental Biologists","title":"Mechanisms of development","title_sort":"Mechanisms of development"}],"physDesc":[{"extent":"Online-Ressource"}],"part":{"year":"2013","extent":"9","issue":"6","volume":"130","pages":"424-432","text":"130(2013), 6, Seite 424-432"},"language":["eng"],"id":{"zdb":["1466356-9"],"issn":["1872-6356"],"eki":["265784255"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"origin":[{"dateIssuedDisp":"1990-2020","publisherPlace":"Shannon","dateIssuedKey":"1990","publisher":"Elsevier"}],"recId":"265784255","pubHistory":["33.1990/91 -volume 164 (December 2020)"],"disp":"Dynamic changes in the transcriptional profile of subventricular zone-derived postnatally born neuroblastsMechanisms of development"}],"person":[{"role":"aut","given":"Konstantin","family":"Khodosevich","display":"Khodosevich, Konstantin"},{"role":"aut","family":"Alfonso","display":"Alfonso, Julieta","given":"Julieta"},{"role":"aut","family":"Monyer","display":"Monyer, Hannah","given":"Hannah"}],"physDesc":[{"extent":"9 S."}],"title":[{"title":"Dynamic changes in the transcriptional profile of subventricular zone-derived postnatally born neuroblasts","title_sort":"Dynamic changes in the transcriptional profile of subventricular zone-derived postnatally born neuroblasts"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"eki":["1580107729"],"doi":["10.1016/j.mod.2012.11.003"]},"language":["eng"],"origin":[{"dateIssuedKey":"2013","dateIssuedDisp":"2013"}],"note":["Available online 5 December 2012","Gesehen am 16.08.2018"],"recId":"1580107729","name":{"displayForm":["Konstantin Khodosevich, Julieta Alfonso, Hannah Monyer"]}} | ||
| SRT | |a KHODOSEVICDYNAMICCHA2013 | ||