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Engineering and evolution of synthetic Adeno-associated virus (AAV) gene therapy vectors via DNA family shuffling

We demonstrate the basic technique to molecularly engineer and evolve synthetic Adeno-associated viral (AAV) gene therapy vectors via...

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Bibliographic Details
Main Authors: Kienle, Eike (Author) , Senís Herrero, Elena (Author) , Börner, Kathleen (Author) , Niopek, Dominik (Author) , Wiedtke, Ellen (Author) , Große, Stefanie (Author) , Grimm, Dirk (Author)
Format: Article (Journal) Video
Language:English
Published: 4/02/2012
In: JoVE. Video journal
Year: 2012, Issue: 62
ISSN:1940-087X
DOI:10.3791/3819
Subjects:
Film
Online Access:Verlag, Volltext: http://dx.doi.org/10.3791/3819
Verlag, Volltext: https://www.jove.com/video/3819/engineering-evolution-synthetic-adeno-associated-virus-aav-gene
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Author Notes:Eike Kienle, Elena Senís, Kathleen Börner, Dominik Niopek, Ellen Wiedtke, Stefanie Grosse, Dirk Grimm

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