Effects of 12-week resistance training during radiotherapy in breast cancer patients
Exercise is considered to be an effective supportive treatment approach in breast cancer (BC) patients. We conducted a randomized controlled trial to assess the efficacy of a 12-week PRT during radiotherapy. Strength performance was assessed by maximal isokinetic peak torque (MIPT) in two different...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
|
| In: |
Scandinavian journal of medicine & science in sports
Year: 2016, Volume: 27, Issue: 11, Pages: 1500-1510 |
| ISSN: | 1600-0838 |
| DOI: | 10.1111/sms.12777 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1111/sms.12777 Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/sms.12777 
|
| Author Notes: | J. Wiskemann, M.E. Schmidt, O. Klassen, J. Debus, C.M. Ulrich, K. Potthoff, K. Steindorf |
| Summary: | Exercise is considered to be an effective supportive treatment approach in breast cancer (BC) patients. We conducted a randomized controlled trial to assess the efficacy of a 12-week PRT during radiotherapy. Strength performance was assessed by maximal isokinetic peak torque (MIPT) in two different angular velocities (60°/s and 180°/s) and maximal voluntary isometric contraction for shoulder external and internal rotation, as well as for knee extension and flexion were assessed pre- and post-intervention in 146 patients randomized to PRT or a control group. Statistical analyses were based on analysis of covariance models for the individual changes from baseline to week 13. Intention-to-treat analyses showed significant between-group differences favoring the exercise group (EX) for MIPT in knee flexion and shoulder internal and external rotation (P < 0.05). Subgroup analyses showed borderline significant differences with regard to pretreatment history, revealing that pretreated chemotherapy patients tend to benefit more from PRT than patients without chemotherapy (P = 0.06). Strength gain at the operated arm was significantly higher than at the non-operated arm in EX. PRT was efficacious in increasing upper and lower limb strength in BC patients undergoing adjuvant radiotherapy. Patients with restrictions due to breast cancer-related surgery and pretreated with chemotherapy might benefit the most. |
|---|---|
| Item Description: | First published: 05 October 2016 Gesehen am 27.08.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1600-0838 |
| DOI: | 10.1111/sms.12777 |