The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis
Malignant astrocytomas are highly aggressive brain tumours with poor prognosis. While a number of structural genomic changes and dysregulation of signalling pathways in gliomas have been described, the identification of biomarkers and druggable targets remains an important task for novel diagnostic...
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| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2012
|
| In: |
EMBO molecular medicine
Year: 2012, Volume: 4, Issue: 1, Pages: 38-51 |
| ISSN: | 1757-4684 |
| DOI: | 10.1002/emmm.201100186 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1002/emmm.201100186 |
| Author Notes: | Iris Augustin, Violaine Goidts, Angelika Bongers, Grainne Kerr, Gordon Vollert, Bernhard Radlwimmer, Christian Hartmann, Christel Herold-Mende, Guido Reifenberger, Andreas von Deimling, Michael Boutros |
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