The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis

Malignant astrocytomas are highly aggressive brain tumours with poor prognosis. While a number of structural genomic changes and dysregulation of signalling pathways in gliomas have been described, the identification of biomarkers and druggable targets remains an important task for novel diagnostic...

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Main Authors: Augustin, Iris (Author) , Goidts, Violaine (Author) , Kerr, Grainne (Author) , Radlwimmer, Bernhard (Author) , Hartmann, Christian (Author) , Herold-Mende, Christel (Author) , Deimling, Andreas von (Author) , Boutros, Michael (Author)
Format: Article (Journal)
Language:English
Published: 2012
In: EMBO molecular medicine
Year: 2012, Volume: 4, Issue: 1, Pages: 38-51
ISSN:1757-4684
DOI:10.1002/emmm.201100186
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1002/emmm.201100186
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Author Notes:Iris Augustin, Violaine Goidts, Angelika Bongers, Grainne Kerr, Gordon Vollert, Bernhard Radlwimmer, Christian Hartmann, Christel Herold-Mende, Guido Reifenberger, Andreas von Deimling, Michael Boutros
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