e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients
BackgroundThe Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is an established 10-point quantitative topographic computed tomography scan score to assess early ischemic changes. We performed a non-inferiority trial between the e-ASPECTS software and neuroradiologists in scoring ASP...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
|
| In: |
International journal of stroke
Year: 2016, Volume: 12, Issue: 6, Pages: 615-622 |
| ISSN: | 1747-4949 |
| DOI: | 10.1177/1747493016681020 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1177/1747493016681020 Verlag, Volltext: https://doi.org/10.1177/1747493016681020 
|
| Author Notes: | Simon Nagel, Devesh Sinha, Diana Day, Wolfgang Reith, René Chapot, Panagiotis Papanagiotou, Elizabeth A Warburton, Paul Guyler, Sharon Tysoe, Klaus Fassbender, Silke Walter, Marco Essig, Jens Heidenrich, Angelos A Konstas, Michael Harrison, Michalis Papadakis, Eric Greveson, Olivier Joly, Stephen Gerry, Holly Maguire, Christine Roffe, James Hampton-Till, Alastair M Buchan and Iris Q Grunwald |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1580648568 | ||
| 003 | DE-627 | ||
| 005 | 20220815001421.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180904r20172016xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1177/1747493016681020 |2 doi | |
| 035 | |a (DE-627)1580648568 | ||
| 035 | |a (DE-576)510648568 | ||
| 035 | |a (DE-599)BSZ510648568 | ||
| 035 | |a (OCoLC)1341018042 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Nagel, Simon |d 1974- |e VerfasserIn |0 (DE-588)129036072 |0 (DE-627)38788775X |0 (DE-576)297460218 |4 aut | |
| 245 | 1 | 0 | |a e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients |c Simon Nagel, Devesh Sinha, Diana Day, Wolfgang Reith, René Chapot, Panagiotis Papanagiotou, Elizabeth A Warburton, Paul Guyler, Sharon Tysoe, Klaus Fassbender, Silke Walter, Marco Essig, Jens Heidenrich, Angelos A Konstas, Michael Harrison, Michalis Papadakis, Eric Greveson, Olivier Joly, Stephen Gerry, Holly Maguire, Christine Roffe, James Hampton-Till, Alastair M Buchan and Iris Q Grunwald |
| 264 | 1 | |c 2017 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a First published: December 1, 2016 | ||
| 500 | |a Gesehen am 04.09.2018 | ||
| 520 | |a BackgroundThe Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is an established 10-point quantitative topographic computed tomography scan score to assess early ischemic changes. We performed a non-inferiority trial between the e-ASPECTS software and neuroradiologists in scoring ASPECTS on non-contrast enhanced computed tomography images of acute ischemic stroke patients.MethodsIn this multicenter study, e-ASPECTS and three independent neuroradiologists retrospectively and blindly assessed baseline non-contrast enhanced computed tomography images of 132 patients with acute anterior circulation ischemic stroke. Follow-up scans served as ground truth to determine the definite area of infarction. Sensitivity, specificity, and accuracy for region- and score-based analysis, receiver-operating characteristic curves, Bland-Altman plots and Matthews correlation coefficients relative to the ground truth were calculated and comparisons were made between neuroradiologists and different pre-specified e-ASPECTS operating points. The non-inferiority margin was set to 10% for both sensitivity and specificity on region-based analysis.ResultsIn total 2640 (132 patients???20 regions per patient) ASPECTS regions were scored. Mean time from onset to baseline computed tomography was 146?±?124?min and median NIH Stroke Scale (NIHSS) was 11 (6?17, interquartile range). Median ASPECTS for ground truth on follow-up imaging was 8 (6.5?9, interquartile range). In the region-based analysis, two e-ASPECTS operating points (sensitivity, specificity, and accuracy of 44%, 93%, 87% and 44%, 91%, 85%) were statistically non-inferior to all three neuroradiologists (all p-values <0.003). Both Matthews correlation coefficients for e-ASPECTS were higher (0.36 and 0.34) than those of all neuroradiologists (0.32, 0.31, and 0.3).Conclusionse-ASPECTS was non-inferior to three neuroradiologists in scoring ASPECTS on non-contrast enhanced computed tomography images of acute stroke patients. | ||
| 534 | |c 2016 | ||
| 773 | 0 | 8 | |i Enthalten in |t International journal of stroke |d London : Sage, 2005 |g 12(2017), 6, Seite 615-622 |h Online-Ressource |w (DE-627)503720291 |w (DE-600)2211666-7 |w (DE-576)306832739 |x 1747-4949 |7 nnas |a e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients |
| 773 | 1 | 8 | |g volume:12 |g year:2017 |g number:6 |g pages:615-622 |g extent:8 |a e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1177/1747493016681020 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://doi.org/10.1177/1747493016681020 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180904 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 129036072 |a Nagel, Simon |m 129036072:Nagel, Simon |d 910000 |d 911100 |e 910000PN129036072 |e 911100PN129036072 |k 0/910000/ |k 1/910000/911100/ |p 1 |x j | ||
| 999 | |a KXP-PPN1580648568 |e 3024682201 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"origin":[{"dateIssuedDisp":"2017","dateIssuedKey":"2017"}],"id":{"doi":["10.1177/1747493016681020"],"eki":["1580648568"]},"language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"person":[{"given":"Simon","display":"Nagel, Simon","family":"Nagel","role":"aut"}],"physDesc":[{"extent":"8 S."}],"title":[{"title":"e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients","title_sort":"e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients"}],"relHost":[{"titleAlt":[{"title":"official journal of the International Stroke Society"}],"title":[{"subtitle":"official journal of the World Stroke Organization","title":"International journal of stroke","title_sort":"International journal of stroke"}],"physDesc":[{"extent":"Online-Ressource"}],"part":{"text":"12(2017), 6, Seite 615-622","pages":"615-622","volume":"12","issue":"6","extent":"8","year":"2017"},"id":{"doi":["10.1111/(ISSN)1747-4949"],"eki":["503720291"],"issn":["1747-4949"],"zdb":["2211666-7"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"origin":[{"publisher":"Sage ; Blackwell ; Wiley-Blackwell","dateIssuedDisp":"21 November 2005-","publisherPlace":"London ; Oxford [u.a.] ; Oxford [u.a.]"}],"recId":"503720291","pubHistory":["Volume 1, issue 1 (February 2006)-"],"note":["Gesehen am 10.02.2021"],"disp":"e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patientsInternational journal of stroke"}],"name":{"displayForm":["Simon Nagel, Devesh Sinha, Diana Day, Wolfgang Reith, René Chapot, Panagiotis Papanagiotou, Elizabeth A Warburton, Paul Guyler, Sharon Tysoe, Klaus Fassbender, Silke Walter, Marco Essig, Jens Heidenrich, Angelos A Konstas, Michael Harrison, Michalis Papadakis, Eric Greveson, Olivier Joly, Stephen Gerry, Holly Maguire, Christine Roffe, James Hampton-Till, Alastair M Buchan and Iris Q Grunwald"]},"recId":"1580648568","note":["First published: December 1, 2016","Gesehen am 04.09.2018"]} | ||
| SRT | |a NAGELSIMONEASPECTSSO2017 | ||