Direct access to isoxazolino and isoxazolo benzazepines from 2-((hydroxyimino)methyl)benzoic acid via a post-Ugi heteroannulation
A diversity-oriented access to isoxazolino and isoxazolo benzazepines is elaborated via a post-Ugi heteroannulation involving intramolecular 1,3-dipolar cycloaddition reaction of nitrile oxides with alkenes and alkynes. This sequence offers an interesting multicomponent entry to a library of isoxazo...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
20 Jun 2017
|
| In: |
Organic & biomolecular chemistry
Year: 2017, Jahrgang: 15, Heft: 27, Pages: 5737-5742 |
| ISSN: | 1477-0539 |
| DOI: | 10.1039/C7OB01142C |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1039/C7OB01142C Verlag, Volltext: https://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob01142c 
|
| Verfasserangaben: | Saeed Balalaie, Mohammad Shamakli, Ali Nikbakht, Nahid S. Alavijeh, Frank Rominger, Shahnaz Rostamizadeh and Hamid Reza Bijanzadeh |
| Zusammenfassung: | A diversity-oriented access to isoxazolino and isoxazolo benzazepines is elaborated via a post-Ugi heteroannulation involving intramolecular 1,3-dipolar cycloaddition reaction of nitrile oxides with alkenes and alkynes. This sequence offers an interesting multicomponent entry to a library of isoxazolino and isoxazolo benzazepines under mild reaction conditions in good to excellent yields. |
|---|---|
| Beschreibung: | Gesehen am 05.09.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1477-0539 |
| DOI: | 10.1039/C7OB01142C |