The PAZOREAL noninterventional study to assess effectiveness and safety of pazopanib and everolimus in the changing metastatic renal cell carcinoma treatment landscape
VEGFR and mTOR inhibitors are broadly used in metastatic renal cell carcinoma (mRCC) therapy, and sequential first-line pazopanib (VEGFR inhibitor) and second-line everolimus (mTOR inhibitor) is a standard treatment option. Nivolumab and lenvatinib/everolimus combination was recently approved in Eur...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
19 May 2017
|
| In: |
Future oncology
Year: 2017, Jahrgang: 13, Heft: 17, Pages: 1463-1471 |
| ISSN: | 1744-8301 |
| DOI: | 10.2217/fon-2017-0083 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.2217/fon-2017-0083 Verlag, Volltext: https://www.futuremedicine.com/doi/10.2217/fon-2017-0083 |
| Verfasserangaben: | Peter J Goebell, Christian Doehn, Carsten Grüllich, Viktor Grünwald, Thomas Steiner, Rainer Ehneß & Manfred Welslau |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 158075905X | ||
| 003 | DE-627 | ||
| 005 | 20220815003302.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180907s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.2217/fon-2017-0083 |2 doi | |
| 035 | |a (DE-627)158075905X | ||
| 035 | |a (DE-576)51075905X | ||
| 035 | |a (DE-599)BSZ51075905X | ||
| 035 | |a (OCoLC)1341018170 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Goebell, Peter Jürgen |d 1967- |e VerfasserIn |0 (DE-588)12273064X |0 (DE-627)706018834 |0 (DE-576)293397899 |4 aut | |
| 245 | 1 | 4 | |a The PAZOREAL noninterventional study to assess effectiveness and safety of pazopanib and everolimus in the changing metastatic renal cell carcinoma treatment landscape |c Peter J Goebell, Christian Doehn, Carsten Grüllich, Viktor Grünwald, Thomas Steiner, Rainer Ehneß & Manfred Welslau |
| 264 | 1 | |c 19 May 2017 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 07.09.2018 | ||
| 520 | |a VEGFR and mTOR inhibitors are broadly used in metastatic renal cell carcinoma (mRCC) therapy, and sequential first-line pazopanib (VEGFR inhibitor) and second-line everolimus (mTOR inhibitor) is a standard treatment option. Nivolumab and lenvatinib/everolimus combination was recently approved in Europe for use in mRCC after previous therapy. Prospective routine data on sequential therapy including nivolumab and/or lenvatinib are missing. This is a prospective, noninterventional study, which evaluates the effectiveness, tolerability, safety and quality of life following 450 patients with mRCC starting either on pazopanib as first-line therapy or third-line everolimus plus/minus lenvatinib following nivolumab. Adults with histologically confirmed mRCC of any subtype, who have a life expectancy of at least 6 months, are eligible. | ||
| 700 | 1 | |a Grüllich, Carsten |d 1965- |e VerfasserIn |0 (DE-588)14101914X |0 (DE-627)624500985 |0 (DE-576)321797981 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Future oncology |d London : Taylor & Francis, 2005 |g 13(2017), 17, Seite 1463-1471 |h Online-Ressource |w (DE-627)484405055 |w (DE-600)2184533-5 |w (DE-576)398100217 |x 1744-8301 |7 nnas |a The PAZOREAL noninterventional study to assess effectiveness and safety of pazopanib and everolimus in the changing metastatic renal cell carcinoma treatment landscape |
| 773 | 1 | 8 | |g volume:13 |g year:2017 |g number:17 |g pages:1463-1471 |g extent:9 |a The PAZOREAL noninterventional study to assess effectiveness and safety of pazopanib and everolimus in the changing metastatic renal cell carcinoma treatment landscape |
| 856 | 4 | 0 | |u http://dx.doi.org/10.2217/fon-2017-0083 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://www.futuremedicine.com/doi/10.2217/fon-2017-0083 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180907 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 14101914X |a Grüllich, Carsten |m 14101914X:Grüllich, Carsten |d 910000 |e 910000PG14101914X |k 0/910000/ |p 5 | ||
| 999 | |a KXP-PPN158075905X |e 3024871594 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"title":[{"title_sort":"Future oncology","title":"Future oncology"}],"note":["Gesehen am 28.05.2024"],"type":{"bibl":"periodical","media":"Online-Ressource"},"pubHistory":["1.2005 -"],"language":["eng"],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedDisp":"2005-","dateIssuedKey":"2005","publisher":"Taylor & Francis ; Future Medicine Ltd","publisherPlace":"London ; London"}],"id":{"eki":["484405055"],"issn":["1744-8301"],"zdb":["2184533-5"]},"part":{"year":"2017","issue":"17","text":"13(2017), 17, Seite 1463-1471","extent":"9","volume":"13","pages":"1463-1471"},"recId":"484405055","disp":"The PAZOREAL noninterventional study to assess effectiveness and safety of pazopanib and everolimus in the changing metastatic renal cell carcinoma treatment landscapeFuture oncology"}],"note":["Gesehen am 07.09.2018"],"name":{"displayForm":["Peter J Goebell, Christian Doehn, Carsten Grüllich, Viktor Grünwald, Thomas Steiner, Rainer Ehneß & Manfred Welslau"]},"recId":"158075905X","id":{"eki":["158075905X"],"doi":["10.2217/fon-2017-0083"]},"origin":[{"dateIssuedDisp":"19 May 2017","dateIssuedKey":"2017"}],"language":["eng"],"physDesc":[{"extent":"9 S."}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"person":[{"given":"Peter Jürgen","role":"aut","family":"Goebell","display":"Goebell, Peter Jürgen"},{"display":"Grüllich, Carsten","given":"Carsten","role":"aut","family":"Grüllich"}],"title":[{"title":"The PAZOREAL noninterventional study to assess effectiveness and safety of pazopanib and everolimus in the changing metastatic renal cell carcinoma treatment landscape","title_sort":"PAZOREAL noninterventional study to assess effectiveness and safety of pazopanib and everolimus in the changing metastatic renal cell carcinoma treatment landscape"}]} | ||
| SRT | |a GOEBELLPETPAZOREALNO1920 | ||