Lebensqualität von Patienten mit Vestibularisschwannom

BackgroundVestibular schwannoma (VS) is a disease which might affect health-related quality of life (HR-QOL) in a negative manner. For many years, only generic quality of life instruments such as SF-36 were available to measure HR-QOL. However, some years ago, the Penn Acoustic Neuroma Quality Of Li...

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Hauptverfasser: Baumann, Ingo (VerfasserIn) , Plinkert, Peter K. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Deutsch
Veröffentlicht: 01 June 2017
In: HNO
Year: 2017, Jahrgang: 65, Heft: 9, Pages: 719-723
ISSN:1433-0458
DOI:10.1007/s00106-017-0371-7
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1007/s00106-017-0371-7
Verlag, Volltext: https://doi.org/10.1007/s00106-017-0371-7
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Verfasserangaben:I. Baumann, P.K. Plinkert

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520 |a BackgroundVestibular schwannoma (VS) is a disease which might affect health-related quality of life (HR-QOL) in a negative manner. For many years, only generic quality of life instruments such as SF-36 were available to measure HR-QOL. However, some years ago, the Penn Acoustic Neuroma Quality Of Life (PANQOL) tool, a disease-specific instrument, was developed and validated. It is expected that the application of this instrument will be able to better assess relevant aspects of the HR-QOL of VS patients in the future. A validated German version of the instrument does not exist yet. The disease-specific symptoms most frequently named by patients are headache and dizziness.Results and discussionThe available literature shows that the therapeutic approaches affect HR-QOL differently. In particular, radiation therapy of small and medium-sized tumors has no pronounced negative effects on HR-QOL. However, restrictions after surgery become similar to those after radiotherapy over the course of several years. For large VS with a diameter >3 cm, no guiding data on this aspect are currently available. To clarify the outstanding issues, future prospective studies with long-term follow-up of 10 years and more are desirable. 
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