Effective downsizing but enhanced intratumoral heterogeneity following neoadjuvant sorafenib in patients with non-metastatic renal cell carcinoma
Objectives To evaluate the safety and feasibility of sorafenib prior to surgery for downsizing tumors in patients with nonmetastatic cT1-3 renal tumors together with a characterization of functional intratumoral heterogeneity (ITH).
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| In: |
Langenbeck's archives of surgery
Year: 2017, Jahrgang: 402, Heft: 4, Pages: 637-644 |
| ISSN: | 1435-2451 |
| DOI: | 10.1007/s00423-016-1543-8 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1007/s00423-016-1543-8 Verlag, Volltext: http://link.springer.com/10.1007/s00423-016-1543-8 |
| Verfasserangaben: | Gencay Hatiboglu, Markus Hohenfellner, Aysenur Arslan, Boris Hadaschik, Dogu Teber, Jan Philipp Radtke, Peter Hallscheidt, Yanis Tolstov, Wilfried Roth, Carsten Grüllich, Johannes Huesing, Stefan Duensing, Sascha Pahernik |
| Zusammenfassung: | Objectives To evaluate the safety and feasibility of sorafenib prior to surgery for downsizing tumors in patients with nonmetastatic cT1-3 renal tumors together with a characterization of functional intratumoral heterogeneity (ITH). |
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| Beschreibung: | Gesehen am 11.09.2018 First online: 23 December 2016 |
| Beschreibung: | Online Resource |
| ISSN: | 1435-2451 |
| DOI: | 10.1007/s00423-016-1543-8 |