Effective downsizing but enhanced intratumoral heterogeneity following neoadjuvant sorafenib in patients with non-metastatic renal cell carcinoma
Objectives To evaluate the safety and feasibility of sorafenib prior to surgery for downsizing tumors in patients with nonmetastatic cT1-3 renal tumors together with a characterization of functional intratumoral heterogeneity (ITH).
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
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| In: |
Langenbeck's archives of surgery
Year: 2017, Volume: 402, Issue: 4, Pages: 637-644 |
| ISSN: | 1435-2451 |
| DOI: | 10.1007/s00423-016-1543-8 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1007/s00423-016-1543-8 Verlag, Volltext: http://link.springer.com/10.1007/s00423-016-1543-8 
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| Author Notes: | Gencay Hatiboglu, Markus Hohenfellner, Aysenur Arslan, Boris Hadaschik, Dogu Teber, Jan Philipp Radtke, Peter Hallscheidt, Yanis Tolstov, Wilfried Roth, Carsten Grüllich, Johannes Huesing, Stefan Duensing, Sascha Pahernik |
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| 520 | |a Objectives To evaluate the safety and feasibility of sorafenib prior to surgery for downsizing tumors in patients with nonmetastatic cT1-3 renal tumors together with a characterization of functional intratumoral heterogeneity (ITH). | ||
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